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MUC2 gene

Known as: mucin 2, oligomeric mucus/gel-forming, MUC2, Mucin 2, Oligomeric Mucus/Gel-Forming Gene 
This gene plays a role in the lubrication of mucosal surfaces.
National Institutes of Health

Related topics

Related topics

6 relations
HomeostasisLigand BindingMUC13 geneMUC2 protein, human

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
Micropapillary Carcinoma of Stomach: A Clinicopathologic and Immunohistochemical Study of 11 Cases
Micropapillary carcinoma (MPC) of the stomach is a rare, newly recognized entity, and only 2 patients with this histology have… 
Highly Cited
2004
Highly Cited
2004
Immunophenotypic Differences Between Intestinal-type and Low-grade Papillary Sinonasal Adenocarcinomas: An Immunohistochemical Study of 22 Cases Utilizing CDX2 and MUC2
Nonsalivary sinonasal adenocarcinomas can be divided into low-grade and high-grade tumors. The former are often papillary and the… 
Highly Cited
2003
Highly Cited
2003
N-linked oligosaccharides play a role in disulphide-dependent dimerization of intestinal mucin Muc2.
Within the C-terminal domain of many secretory mucins is a 'cystine knot' (CK), which is needed for dimer formation in the… 
2003
2003
Immunoreactivity of cytokeratins (CK7, CK20) and mucin peptide core antigens (MUC1, MUC2, MUC5AC) in adenocarcinomas, normal and metaplastic tissues of the distal oesophagus, oesophago–gastric…
Aims:  Adenocarcinomas of the distal oesophagus and especially the oesophago–gastric junction have shown an increasing incidence… 
Highly Cited
2001
Highly Cited
2001
The Sp family of transcription factors in the regulation of the human and mouse MUC2 gene promoters.
Modulation of mucin gene expression is an important component both in the early steps of colon cancer development and in later… 
Highly Cited
1999
Highly Cited
1999
Gastrointestinal expression and partial cDNA cloning of murine Muc2.
To help us investigate the role of mucin in the protection of the colonic epithelium in the mouse, we aimed to identify the… 
Highly Cited
1997
Highly Cited
1997
Mucin mRNA Expression in Normal and Vasomotor Inferior Turbinates
Mucins are the major glycoprotein component of respiratory tract secretions. Little is known about their expression in the upper… 
Highly Cited
1997
Highly Cited
1997
MUC1 and MUC2 mucins in flat and polypoid colorectal adenomas.
AIMS: To examine the expression of MUC1 and MUC2 apomucins and distribution of MUC phenotypes (MUC2+/ MUC-, MUC2+/MUC1+, MUC2… 
Highly Cited
1997
Highly Cited
1997
Organization and Regulatory Aspects of the Human Intestinal Mucin Gene (MUC2) Locus*
The human MUC2 gene maps to chromosome 11p15, where three additional mucin genes have been located, and encodes the most abundant… 
Highly Cited
1992
Highly Cited
1992
Second-generation monoclonal antibodies to intestinal MUC2 peptide reactive with colon cancer.
BACKGROUND Antitumor antibodies have traditionally been made to whole tumors or tumor extract. The use of defined synthetic… 
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