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MSH3 gene

Known as: Mismatch repair protein 1, DIVERGENT UPSTREAM PROTEIN, MRP1 
This gene plays a role in DNA mismatch repair and has been implicated in several cancers.
National Institutes of Health

Related topics

Related topics

6 relations
DNA RepairEndometrial CarcinomaIntestinal CancerMismatch Repair

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Nucleosomes around a mismatched base pair are excluded via an Msh2-dependent reaction with the aid of SNF2 family ATPase Smarcad1
Here, Terui et al. studied the mechanisms underlying chromatin remodeling that occurs during MMR. They show that the eukaryotic… 
2017
2017
Inactivation of MSH3 by promoter methylation correlates with primary tumor stage in nasopharyngeal carcinoma
The aim of this study was to investigate the inactivation of the MutS homolog human 3 (MSH3) gene by promoter methylation in… 
2015
2015
MSH 3 rs 26279 polymorphism increases cancer risk : a meta-analysis
Previous studies have investigated the association of mutS homolog 3 (MSH3) rs26279 G > A polymorphism with the risk of different… 
Highly Cited
2011
Highly Cited
2011
Association of low‐risk MSH3 and MSH2 variant alleles with Lynch syndrome: Probability of synergistic effects
Mutations in the MLH1 and MSH2 genes account for a majority of cases of families with Lynch Syndrome. Germ‐line mutations in MSH6… 
2004
2004
Inactivation of the hMSH3 mismatch repair gene in bladder cancer.
2004
2004
MDR1, MRP1 and MRP2 genotypes and in vitro chemosensitivity in Japanese patients with colorectal adenocarcinomas.
In our previous paper, the chemosensitivity of human colorectal adenocarcinoma was evaluated against 12 anticancer drugs… 
2002
2002
Cytogenetic aberrations and heterogeneity of mutations in repeat-containing genes in a colon carcinoma from a patient with hereditary nonpolyposis colorectal cancer.
1999
1999
Cloning of rat MLH1 and expression analysis of MSH2, MSH3, MSH6, and MLH1 during spermatogenesis.
The mismatch repair system has been highly conserved in various species. In eukaryotic cells, the Mut S and Mut L homologues play… 
1995
1995
Loss of expression of the human MSH3 gene in hematological malignancies.
Human MSH3 (hMSH3), previously named human mismatch repair protein 1 (MRP1), is one of the human homologs of the bacterial DNA… 
1992
1992
A GC box in the bidirectional promoter is essential for expression of the human dihydrofolate reductase and mismatch repair protein 1 genes
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