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MS-377

Known as: MS 377 
National Institutes of Health

Papers overview

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2002
2002
Inhibition by sigma receptor ligand, MS-377, of N-methyl-D-aspartate-induced currents in dopamine neurons of the rat ventral tegmental area
Abstract.Rationale: MS-377 [(R)-(+)-1-(4-chlorophenyl)-3-[4-(2-methoxyethyl) piperazin-1-yl]methyl-2-pyrrolidinone L-tartate] is… 
2002
2002
The selective sigma ligand MS-377 attenuates the blockade by phencyclidine of NMDA-induced intracellular calcium.
The role of MS-377, a novel selective sigma1 ligand currently being developed for the treatment of schizophrenia, in modulating… 
2002
2002
Effects of sigma(1) receptor ligand MS-377 on D(2) antagonists-induced behaviors.
(R)-(+)-1-(4-Chlorophenyl)-3-[4-(2-methoxyethyl)piperazin-1-yl]methyl-2-pyrrolidinone L-tartrate (MS-377) is a novel… 
2001
2001
Effects of a novel, selective, σ1-ligand, MS-377, on phencyclidine-induced behaviour
Abstract. Phencyclidine (PCP)-induced head-weaving is inhibited by a novel selective σ1-ligand, (R)-(+)-1-(4-chlorophenyl)-3-[4… 
2000
2000
Binding properties of [3H]MS-377, a novel sigma receptor ligand, to rat brain membranes.
MS-377 ((R)-(+)-1-(4-chlorophenyl)-3-[4-(2-methoxyethyl)piperazin-1-yl]++ +methy l-2-pyrrolidinone L-tartrate) is a novel… 
2000
2000
Effects of sigma(1) receptor ligand, MS-377 on apomorphine- or phencyclidine-induced disruption of prepulse inhibition of acoustic startle in rats.
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