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MRGPRD gene

Known as: MRGPRD, MAS related GPR family member D, MRGD 
 
National Institutes of Health

Related topics

Related topics

1 relation
MRGPRE gene

Papers overview

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2018
2018
Alamandine acts via MrgD to induce AMPK/NO activation against ANG II hypertrophy in cardiomyocytes.
The renin-angiotensin system (RAS) plays a pivotal role in the pathogenesis of cardiovascular diseases. New members of this… Expand
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2017
2017
Distinct behavioral responses evoked by selective optogenetic stimulation of the major TRPV1+ and MrgD+ subsets of C-fibers
Abstract Primary C-fiber nociceptors are broadly divided into peptidergic and nonpeptidergic afferents. TRPV1 is a… Expand
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Highly Cited
2016
Highly Cited
2016
G-Protein–Coupled Receptor MrgD Is a Receptor for Angiotensin-(1–7) Involving Adenylyl Cyclase, cAMP, and Phosphokinase A
Angiotensin (Ang)-(1–7) has cardiovascular protective effects and is the opponent of the often detrimental Ang II within the… Expand
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Review
2015
Review
2015
Angiotensin type 2 receptor (AT2R) and receptor Mas: a complex liaison.
The angiotensin type 2 receptor (AT2R) and the receptor Mas are components of the protective arms of the renin-angiotensin system… Expand
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Highly Cited
2014
Highly Cited
2014
Enhanced excitability of MRGPRA3- and MRGPRD-positive nociceptors in a model of inflammatory itch and pain.
Itch is a common symptom of diseases of the skin but can also accompany diseases of other tissues including the nervous system… Expand
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2014
2014
Reduction of angiotensin A and alamandine vasoactivity in the rabbit model of atherogenesis: differential effects of alamandine and Ang(1‐7)
Novel treatments are necessary to reduce the burden of cardiovascular disease (CVD). Alamandine binds to MrgD and is reported to… Expand
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2012
2012
MRGD, a MAS-related G-protein Coupled Receptor, Promotes Tumorigenisis and Is Highly Expressed in Lung Cancer
To elucidate the function of MAS-related GPCR, member D (MRGD) in cancers, we investigated the in vitro and in vivo oncogenic… Expand
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2010
2010
Development of a FLIPR Assay for the Simultaneous Identification of MrgD Agonists and Antagonists from a Single Screen
MrgD, a member of the Mas-related gene family, is expressed exclusively in small diameter IB4+ neurons in the dorsal root… Expand
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Highly Cited
2007
Highly Cited
2007
MrgD Activation Inhibits KCNQ/M-Currents and Contributes to Enhanced Neuronal Excitability
The recently identified Mas-related gene (Mrg) family of G-protein-coupled receptors is expressed almost exclusively in dorsal… Expand
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Highly Cited
2005
Highly Cited
2005
Cloning and expression of MRG receptors in macaque, mouse, and human.
Members of the MRG family of G-protein coupled receptors (GPCRs) are expressed predominately in small diameter sensory neurons of… Expand
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