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MR1 gene

Known as: MHC-RELATED PROTEIN 1, HLALS, MAJOR HISTOCOMPATIBILITY COMPLEX, CLASS I-LIKE SEQUENCE 
This gene plays a role in antigen presentation.
National Institutes of Health

Related topics

Related topics

1 relation
Immune System Processes

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Production of MR1 Tetramers Loaded with Microbial Ligands.
In lieu of peptides, the monomorphic MHC-I-like molecule MR1 presents small molecule antigens to stimulate a subset of αβ T cells… 
Review
2018
Review
2018
Mucosal‐associated invariant T cell receptor recognition of small molecules presented by MR1
The major histocompatibility complex (MHC) class‐I related molecule MR1 is a monomorphic and evolutionary conserved antigen (Ag… 
2017
2017
The Toll‐like receptor 9 signalling pathway regulates MR1‐mediated bacterial antigen presentation in B cells
Mucosal‐associated invariant T (MAIT) cells are conserved T cells that express a semi‐invariant T‐cell receptor (Vα7.2 in humans… 
Review
2017
Review
2017
MAIT cells and MR1-antigen recognition.
Highly Cited
2016
Highly Cited
2016
Endosomal MR1 Trafficking Plays a Key Role in Presentation of Mycobacterium tuberculosis Ligands to MAIT Cells
Mucosal-Associated Invariant T (MAIT) cells, present in high frequency in airway and other mucosal tissues, have Th1 effector… 
Review
2015
Review
2015
MR1 presentation of vitamin B-based metabolite ligands.
Review
2014
Review
2014
MAITs, MR1 and vitamin B metabolites.
2002
2002
Essential Role for CD40 Ligand Interactions in T Lymphocyte-Mediated Modulation of the Murine Immune Response to Pneumococcal Capsular Polysaccharides1
Protection against infection with pneumococci is provided by anti-capsular polysaccharide (caps-PS) Abs. We investigated whether… 
Highly Cited
2001
Highly Cited
2001
CD8 T CELL-MEDIATED REJECTION OF INTESTINAL ALLOGRAFTS IS RESISTANT TO INHIBITION OF THE CD40/CD154 COSTIMULATORY PATHWAY
Background. Disruption of the CD40/CD154 pathway inhibits rejection in numerous models. The importance of this pathway on… 
2001
2001
CD4+ and CD8+ T Cell Priming for Contact Hypersensitivity Occurs Independently of CD40-CD154 Interactions1
The primary effector cells of contact hypersensitivity (CHS) responses to dintrofluorobenzene (DNFB) are IFN-γ-producing CD8+ T… 
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