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MPV 1248

Known as: MPV-1248 
National Institutes of Health

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1 relation

Broader (1)

atipamezole

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2000
2000
Atipamezole, an imidazoline-type alpha(2)-adrenoceptor inhibitor, binds to human platelets and inhibits their adrenaline-induced aggregation more effectively than yohimbine.
1992
1992
Characterization of [3H]atipamezole as a radioligand for alpha 2-adrenoceptors.
Atipamezole (MPV-1248, 4-(2-ethyl-2,3-dihydro-1H-inden-2-yl)-1H-imidazole), a potent alpha 2-adrenoceptor antagonist, was… 
1990
1990
No involvement of α 2-adrenoceptors in the regulation of basal prolactin secretion in healthy men
Highly Cited
1990
Highly Cited
1990
Pharmacological effects and pharmacokinetics of atipamezole, a novel alpha 2-adrenoceptor antagonist--a randomized, double-blind cross-over study in healthy male volunteers.
1. Single doses (10, 30 and 100 mg) of atipamezole (MPV-1248), a new potent and selective imidazole-type alpha 2-adrenoceptor… 
Highly Cited
1989
Highly Cited
1989
Highly selective and specific antagonism of central and peripheral alpha 2-adrenoceptors by atipamezole.
The potency, selectivity and specificity of atipamezole [MPV-1248, 4-(2-ethyl-2,3-dihydro-1H-inden-2-yl)-1H-imidazole], as an… 
1989
1989
Pharmacologic characterization of the receptor mediating the hypnotic action of dexmedetomidine.
The anesthetic-reducing property of medetomidine far exceeds that seen with other alpha 2-adrenergic agonists (e.g., clonidine… 
1988
1988
Behavioural and neurochemical effects of antipamezole, a novel alpha 2-adrenoceptor antagonist.
The effects of antipamezole (MPV-1248), a novel selective and specific alpha 2-adrenoceptor antagonist, were studied on monoamine… 
1986
1986
Comparison of free MHPG in rat cerebrospinal fluid with free and conjugated MHPG in brain tissue: effects of drugs modifying noradrenergic transmission.
1986
1986
Preliminary report on the cardiorespiratory effects of the antagonist to detomidine, MPV-1248.
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