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MPHOSPH8 gene

Known as: MPHOSPH8, HSMPP8, MPP8 
National Institutes of Health

Papers overview

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2019
2019
The H3K9 Methylation Writer SETDB1 and Its Reader MPP8 Cooperate to Silence Satellite DNA Repeats in Mouse Embryonic Stem Cells
SETDB1 (SET Domain Bifurcated histone lysine methyltransferase 1) is a key lysine methyltransferase (KMT) required in embryonic… 
Highly Cited
2018
Highly Cited
2018
HIV-2/SIV viral protein X counteracts HUSH repressor complex
To evade host immune defences, human immunodeficiency viruses 1 and 2 (HIV-1 and HIV-2) have evolved auxiliary proteins that… 
Highly Cited
2018
Highly Cited
2018
Primate immunodeficiency virus Vpx and Vpr counteract transcriptional repression of proviruses by the HUSH complex
Host factors that silence provirus transcription in CD4+ memory T cells help HIV-1 escape eradication by the host immune system… 
2015
2015
MPP8 and SIRT1 crosstalk in E‐cadherin gene silencing and epithelial–mesenchymal transition
As a critical developmental process, epithelial–mesenchymal transition (EMT) involves complex transcriptional reprogramming and… 
2015
2015
MPP 8 and SIRT 1 crosstalk in E-cadherin gene silencing and epithelial – mesenchymal transition
As a critical developmental process, epithelial–mesenchymal transition (EMT) involves complex transcriptional reprogramming and… 
2013
2013
Mitotic phosphorylation of MPP8 by cyclin-dependent kinases regulates chromatin dissociation.
2011
2011
Structural insights for MPP8 chromodomain interaction with histone H3 lysine 9: potential effect of phosphorylation on methyl-lysine binding.
Highly Cited
2010
Highly Cited
2010
Methyl‐H3K9‐binding protein MPP8 mediates E‐cadherin gene silencing and promotes tumour cell motility and invasion
H3K9 methylation has been linked to a variety of biological processes including position‐effect variegation, heterochromatin… 
Highly Cited
2010
Highly Cited
2010
A homogeneous method for investigation of methylation-dependent protein–protein interactions in epigenetics
Methylation of lysine residues on the tails of histone proteins is a major determinant of the transcription state of associated… 
Highly Cited
2003
Highly Cited
2003
A novel nuclear protein, Twa1, and Muskelin comprise a complex with RanBPM.
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