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MNRP1685A

Known as: Anti-Neuropilin-1 Monoclonal Antibody MNRP1685A 
A human IgG1 monoclonal antibody directed against neuropilin-1 (NRP1), with potential antiangiogenic and antineoplastic activities. Upon intravenous… Expand
National Institutes of Health

Papers overview

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2018
2018
The tumor vasculature differs from normal blood vessels in morphology, composition and stability. Here, we describe a novel tumor… Expand
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2014
2014
PurposeMNRP1685A is a human monoclonal antibody that blocks binding of vascular endothelial growth factor (VEGF), VEGF-B, and… Expand
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2014
2014
SummaryThe human monoclonal antibody MNRP1685A targets the VEGF binding domain of neuropilin-1 (NRP1), a multi-domain receptor… Expand
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2014
2014
Neuropilin-1, a transmembrane receptor entailed in wide range of human tumour cell lines and diverse neoplasms, mediates the… Expand
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2012
2012
PurposeTo compare the pharmacokinetics (PK) of MNRP1685A, a human monoclonal antibody (mAb) against neuropilin-1 (NRP1), in mice… Expand
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2012
2012
BACKGROUND AND PURPOSE Neuropilin-1 (NRP1) is a VEGF receptor that is widely expressed in normal tissues and is involved in… Expand
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2012
2012
PURPOSE MNRP1685A is a monoclonal antibody to neuropilin-1 (NRP1). We evaluated blood-based pharmacodynamic biomarkers of… Expand
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2011
2011
e13598 Background: Neuropilin-1 (NRP1), a high affinity receptor for members of the VEGF family, is expressed on endothelial… Expand
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2010
2010
3014 Background: Anti-NRP1 specifically targets neuropilin-1 (NRP1), a multi-domain receptor known to bind a variety of ligands… Expand
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2005
2005
Neuropilin-1 (NRP-1) was first described as a coreceptor implicated in neuronal guidance that bound members of the semaphorin… Expand
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