Skip to search formSkip to main contentSkip to account menu

MMP11 protein, human

Known as: Matrix Metalloprotease 11, matrix metallopeptidase 11 (stromelysin 3), human, Matrix Metalloproteinase 11 
Stromelysin-3 (488 aa, ~55 kDa) is encoded by the human MMP11 gene. This protein plays a role in extracellular matrix metabolism.
National Institutes of Health

Related topics

Related topics

11 relations
Embryonic DevelopmentEnzyme GeneHydrolysisMMP-11 activity

Broader (1)

Matrix Metalloproteinase 11

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2003
Highly Cited
2003
Identification of Peptide Substrates for Human MMP-11 (Stromelysin-3) Using Phage Display*
The MMP-11 proteinase, also known as stromelysin-3, probably plays an important role in human cancer because MMP-11 is frequently… 
2000
2000
Matrix Metalloproteinases-2, -3, -7, -9 and -10, But Not MMP-11, Are Differentially Expressed in Normal, Benign Tumorigenic and Malignant Human Keratinocyte Cell Lines
Abstract In order to investigate the correlations between constitutive proteinase expression and the degree of tumorigenicity of… 
1999
1999
Stromelysin‐3 (ST‐3): immunohistochemical characterization of the matrix metalloproteinase (MMP)‐11 in benign and malignant skin tumours and other skin disorders
Matrix metalloproteinases (MMP) are involved in remodelling of the extracellular matrix (ECM) proteins suggesting that they play… 
Highly Cited
1998
Highly Cited
1998
Cloning of three Caenorhabditis elegans genes potentially encoding novel matrix metalloproteinases.
Highly Cited
1996
Highly Cited
1996
High levels of stromelysin‐3 correlate with poor prognosis in patients with breast carcinoma
Stromelysin 3 (ST3) is a matrix metalloprotease (MMP) expressed in fibroblast‐like cells of most human invasive carcinomas. In… 
Highly Cited
1996
Highly Cited
1996
Transient expression of stromelysin-3 mRNA in the amphibian small intestine during metamorphosis
Abstract.It has been suggested that a matrix metalloproteinase, stromelysin-3 (ST3), is an important enzyme for epithelial… 
Highly Cited
1995
Highly Cited
1995
Stromelysin-3 is overexpressed by stromal elements in primary non-small cell lung cancers and regulated by retinoic acid in pulmonary fibroblasts.
Stromelysin-3 (STR-3) is a recently characterized matrix metalloproteinase (MMP) that was cloned on the basis of differential… 
Highly Cited
1995
Highly Cited
1995
Structure and Promoter Characterization of the Human Stromelysin-3 Gene (*)
In the present study, we have isolated the human stromelysin-3 (ST3) gene which encodes a matrix metalloproteinase (MMP… 
Review
1994
Review
1994
Stromelysin-3 gene expression in human cancer: an overview.
Stromelysin-3 (ST3) belongs to the family of matrix metalloproteinases, a group of proteolytic enzymes which are believed to play… 
1994
1994
Increased expression of stromelysin‐3 in basal cell carcinomas
We examined the expression of two groups of matrix metalloproteinases (MMPs), stromelysin and interstitial collagenase, in human… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)