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MLPH gene

Known as: Slac-2a, ln, exophilin-3 
National Institutes of Health

Related topics

Related topics

1 relation
melanophilin

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2007
2007
Identification of a Minimal Myosin Va Binding Site within an Intrinsically Unstructured Domain of Melanophilin*
Myosin V is a molecular motor that transports a variety of cellular cargo, including organelles, vesicles, and messenger RNA. The… 
Highly Cited
2006
Highly Cited
2006
Rab7 and Rab27a control two motor protein activities involved in melanosomal transport.
Melanosomes are lysosome-related organelles that synthesize, store and transport melanin. In epidermal melanocytes, melanosomes… 
Highly Cited
2006
Highly Cited
2006
In vitro reconstitution of a transport complex containing Rab27a, melanophilin and myosin Va
Highly Cited
2005
Highly Cited
2005
Activation of Myosin Va Function by Melanophilin, a Specific Docking Partner of Myosin Va*
It is known that melanophilin is a myosin Va-targeting molecule that links myosin Va and the cargo vesicles in cells. Here we… 
Highly Cited
2005
Highly Cited
2005
Melanophilin and myosin Va track the microtubule plus end on EB1
In mouse melanocytes, myosin Va is recruited onto the surface of melanosomes by a receptor complex containing Rab27a that is… 
Highly Cited
2003
Highly Cited
2003
Characterization of the Molecular Defects in Rab27a, Caused by RAB27A Missense Mutations Found in Patients with Griscelli Syndrome*
Rab27a plays a pivotal role in the transport of melanosomes to dendrite tips of melanocytes and mutations in RAB27A, which impair… 
Highly Cited
2002
Highly Cited
2002
Slac2-a/Melanophilin, the Missing Link between Rab27 and Myosin Va
Myosin Va is a member of the unconventional class V myosin family, and a mutation in themyosin Va gene causes pigment granule… 
Highly Cited
2002
Highly Cited
2002
A Family of Rab27-binding Proteins
The Rab27a GTPase regulates diverse processes involving lysosome-related organelles, including melanosome motility in melanocytes… 
Highly Cited
2002
Highly Cited
2002
Melanophilin directly links Rab27a and myosin Va through its distinct coiled‐coil regions
Highly Cited
2001
Highly Cited
2001
Mutations in Mlph, encoding a member of the Rab effector family, cause the melanosome transport defects observed in leaden mice
The d, ash, and ln coat color mutations provide a unique model system for the study of vesicle transport in mammals. All three… 
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