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MK-8742

National Institutes of Health

Papers overview

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2018
2018
Antiviral Activity, Safety, and Tolerability of Multiple Ascending Doses of Elbasvir or Grazoprevir in Participants Infected With Hepatitis C Virus Genotype-1 or -3.
2016
2016
Alkyl substituted aminal derivatives of HCV NS5A inhibitor MK-8742.
2016
2016
Aryl or heteroaryl substituted aminal derivatives of HCV NS5A inhibitor MK-8742.
2015
2015
Effi cacy and safety of grazoprevir ( MK-5172 ) and elbasvir ( MK-8742 ) in patients with hepatitis C virus and HIV co-infection ( C-EDGE CO-INFECTION ) : a non-randomised , open-label trial
Bonn University Hospital, Bonn, Germany (Prof J K Rockstroh MD); Chelsea and Westminster Hospital, London, UK (M Nelson MD… 
2015
2015
O001 : C-salvage: grazoprevir (GZR; MK-5172), elbasvir (EBR; MK-8742) and ribavirin (RBV) for chronic hcv-genotype 1 (GT1) infection after failure of direct-acting antiviral (DAA) therapy
2015
2015
P0910 : No evidence of pharmacokinetic drug–drug interaction in healthy subjects between coadministered grazoprevir (MK-5172)/elbasvir (MK-8742) and sofosbuvir
2014
2014
Efficacy and safety of MK-5172 and MK-8742 +/- ribavirin in hepatitis C genotype 1 infected patients with cirrhosis or previous null response : Final results of the C-WORTHY Study (Parts A and B)
Efficacy and safety of MK-5172 and MK-8742 +/- ribavirin in hepatitis C genotype 1 infected patients with cirrhosis or previous… 
2014
2014
Age and Gender Effects on the Pharmacokinetics of HCV NS5A Inhibitor MK-8742
Background: MK-8742 is a potent, once-daily, inhibitor of the hepatitis C virus (HCV) nonstructural protein NS5A being developed… 
2013
2013
Safety and pharmacokinetics of single and multiple oral doses of MK-8742, an HCV NS5A inhibitor, in healthy subjects
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