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MK-8228

National Institutes of Health

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letermovir

Papers overview

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2015
2015
In Vitro Drug Combination Studies of Letermovir (AIC246, MK-8228) with Approved Anti-Human Cytomegalovirus (HCMV) and Anti-HIV Compounds in Inhibition of HCMV and HIV Replication
ABSTRACT Despite modern prevention and treatment strategies, human cytomegalovirus (HCMV) remains a common opportunistic pathogen… 
2015
2015
Voriconazole, but not Posaconazole, Exposures Are Significantly Decreased by Letermovir (MK-8228) Coadministration in Healthy Subjects
Introduction: Letermovir (MK-8228) is a potent inhibitor of the cytomegalovirus (CMV) terminase complex that is being developed… 
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