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MK-7655
Known as:
relebactam
National Institutes of Health
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Related topics
Related topics
2 relations
Broader (2)
Azabicyclo Compounds
beta-Lactamase Inhibitors
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Activity of imipenem-relebactam against multidrug-resistant Pseudomonas aeruginosa from the United States - SMART 2015-2017.
J. Karlowsky
,
S. Lob
,
K. Young
,
M. Motyl
,
D. Sahm
Diagnostic microbiology and infectious disease
2019
Corpus ID: 182948671
2019
2019
Potentiation of imipenem by relebactam for Pseudomonas aeruginosa from bacteraemia and respiratory infections.
C. Horner
,
S. Mushtaq
,
D. Livermore
Journal of Antimicrobial Chemotherapy
2019
Corpus ID: 139101969
BACKGROUND Imipenem resistance in Pseudomonas aeruginosa most often entails loss of the 'carbapenem-specific' porin OprD; more…
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2019
2019
Role of transporters in the disposition of a novel β-lactamase inhibitor: relebactam (MK-7655).
G. Chan
,
R. Houle
,
+4 authors
X. Chu
Journal of Antimicrobial Chemotherapy
2019
Corpus ID: 84185635
OBJECTIVES To identify the transporters involved in renal elimination of relebactam, and to assess the potential of relebactam as…
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2019
2019
Antibacterial effect of imipenem/relebactam on aerobic Gram-negative bacilli: in vitro simulations of 7 or 14 day human exposures.
A. Noel
,
K. Bowker
,
M. Attwood
,
A. Macgowan
Journal of Antimicrobial Chemotherapy
2019
Corpus ID: 146035998
OBJECTIVES We assessed the antibacterial effect of human simulations of dosing with imipenem/relebactam (with or without amikacin…
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2019
2019
Faculty Opinions recommendation of Imipenem-Relebactam and Meropenem-Vaborbactam: Two Novel Carbapenem-β-Lactamase Inhibitor Combinations.
Richard Watkins
Faculty Opinions – Post-Publication Peer Review…
2019
Corpus ID: 86734029
2019
2019
Highly selective and wash-free visualization of resistant bacteria with a relebactam-derived fluorogenic probe.
Yefeng Chen
,
Minqiu Xu
,
+6 authors
Hexin Xie
Chemical Communications
2019
Corpus ID: 198131443
Reported herein is a relebactam-derived fluorogenic reagent for covalent labeling of serine β-lactamases (SBLs), which are the…
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2018
2018
In Vivo Efficacy of Relebactam (MK-7655) in Combination with Imipenem-Cilastatin in Murine Infection Models
M. Powles
,
Andrew M. Galgoci
,
+7 authors
K. Young
Antimicrobial Agents and Chemotherapy
2018
Corpus ID: 46936145
The World Health Organization has identified antimicrobial resistance as a global public health threat since the prevalence and…
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Review
2018
Review
2018
Neue β‑Laktam-Antibiotika und β‑Laktamase-Inhibitoren gegen multiresistente Gram-negative Erreger
A. Mischnik
,
C. Lübbert
,
N. Mutters
Der Internist
2018
Corpus ID: 52877424
ZusammenfassungHintergrundDie rasche Zunahme multiresistenter Gram-negativer Erreger (MRGN) ist ein drängendes und weitgehend…
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2018
2018
1339. Results for the Supplemental Microbiological Modified Intent-to-Treat (SmMITT) Population of the RESTORE-IMI 1 Trial of Imipenem/Cilastatin/Relebactam (IMI/REL) vs. Imipenem/Cilastatin Plus…
K. Kaye
,
T. File
,
+10 authors
Amanda Paschke
Open Forum Infectious Diseases
2018
Corpus ID: 53815709
Abstract Background Clinical trials of new antibacterial agents in patients with carbapenem-resistant infections are critical but…
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Review
2015
Review
2015
[New antibacterial agents on the market and in the pipeline].
W. Kern
Der Internist
2015
Corpus ID: 34076115
After some years of stagnation there have been several new successful developments in the field of antibacterial agents. Most of…
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