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MK 507

Known as: MK-507 
National Institutes of Health

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1 relation

Broader (1)

dorzolamide

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1999
1999
Comparison of intraocular pressure lowering by topical and systemic carbonic anhydrase inhibitors in the rabbit.
We compared the effect on intraocular pressure (IOP) of maximal doses of a topical carbonic anhydrase inhibitor (CAI) at acidic… 
1996
1996
A clinical trial of MK-507, Trusopt, for raised intraocular pressure--the Australian experience.
BACKGROUND Since the introduction of carbonic anhydrase inhibitors, a topical preparation has been sought to avoid the… 
1995
1995
Long‐term Glaucoma Treatment with MK‐507, Dorzolamide, a Topical Carbonic Anhydrase Inhibitor
PurposeThe purpose of this study was to examine the long-term efficacy and safety of dorzolamide (a topical carbonic anhydrase… 
1994
1994
Effect of MK-507 on aqueous humor dynamics in normal human eyes.
The effects of the topical carbonic anhydrase inhibitor, MK-507, on aqueous humor dynamics were studied in 6 normal volunteers… 
1994
1994
3-substituted thieno[2,3-b][1,4]thiazine-6-sulfonamides. A novel class of topically active carbonic anhydrase inhibitors.
3-Aminoalkyl derivatives of thieno[2,3-b][1,4]thiazine-6-sulfonamide were prepared for evaluation as topically active ocular… 
1994
1994
[Effect of topical carbonic anhydrase inhibitor (MK-507) on intraocular pressure of normal human eyes].
The effects of topical carbonic anhydrase inhibitor (MK-507) on intraocular pressure (IOP) were studied in normal human eyes. The… 
Review
1992
Review
1992
Topical carbonic anhydrase inhibitors: a new perspective in glaucoma therapy.
Oral carbonic anhydrase inhibitors have been used extensively in the treatment of all types of glaucoma. These agents reduce… 
Highly Cited
1991
Highly Cited
1991
MK-507 versus sezolamide. Comparative efficacy of two topically active carbonic anhydrase inhibitors.
1991
1991
[MK-507 (L-671 152): local tolerance and effectiveness of a new local carbonic anhydrase inhibitor in healthy probands].
A three-dose, randomized, double-blind parallel, placebo-controlled ocular tolerancy study was undertaken in 24 healthy, normal… 
1991
1991
The effect of cyclooxygenase inhibition on the ocular hypotensive action of topical carbonic anhydrase inhibitors in rabbits.
Experiments were undertaken in normal albino rabbits to determine if cyclooxygenase inhibition by nonsteroidal anti-inflammatory… 
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