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MIR21 gene

Known as: MIR21, MIR-21, hsa-mir-21 
This gene is involved in the regulation of gene expression and plays an oncogenic role in hepatocellular, breast, esophageal, gastric, pancreatic… 
National Institutes of Health

Related topics

Related topics

12 relations
Brainstem gliomaBreast CarcinomaEsophageal carcinomaGlioblastoma

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
The miR-21 / PDCD 4 / AP-1 feedback loop function as a driving force for renal fibrogenesis
Renal fibrosis is a final common pathway of chronic kidney disease. Sustained activation of fibroblast is considered to play a… 
2017
2017
Expression of miR-21 and Its Acat 1 , Armcx 1 , and Pten Target Genes in Liver of Female Rats Treated with DDT and Benzo [ a ] pyrene
⎯MiR-21 is the most studied cancer-promoting oncomiR, which target numerous tumor suppressor genes associated with proliferation… 
2017
2017
MiR-21 suppresses ox-LDL-induced HUVECs apoptosis by targeting PDCD4.
This study was to investigate the effects of microRNA-21 (miR-21) on ox-LDL-induced HUVECs apoptosis. MTT assay was performed to… 
2016
2016
Impact of Clotting Condition on the Measurement of Circulating MicroRNAs in Serum.
BACKGROUND Circulating microRNA (miRNA) biomarkers have attracted attention as possible blood-based indicators of disease… 
2015
2015
Original Article Differential expression of miRNAs in uterine leiomyoma and adjacent myometrium of different races
African American (black) women have a higher rate, larger size and worse morbidity of uterine leiomyoma- ta (fibroids) than white… 
Highly Cited
2014
Highly Cited
2014
Expression of serum miR-16, let-7f, and miR-21 in patients with hepatocellular carcinoma and their clinical significances.
BACKGROUND Recent studies showed that serum microRNAs were aberrantly expressed in cancers, including hepatocellular carcinoma… 
2014
2014
Modulation of FoxO 1 Expression by miR-21 to Promote Growth of Pancreatic Ductal Adenocarcinoma
Background: Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal primary tumors in humans, with undetermined… 
2012
2012
MiRNA-21 Reverses High Glucose and High Insulin Induced Insulin Resistance in 3 T 3L 1 Adipocytes through Targeting Phosphatase and Tensin
▼ Aims/hypothesis: Our previous study showed there was a change of microRNA (miRNA) expression profi le, and miR-21 was signifi… 
2011
2011
microRNA-21 ORCHESTRATES HIGH GLUCOSE-INDUCED SIGNALS TO TORC 1 FOR RENAL CELL PATHOLOGY IN DIABETES
Hyperglycemia induces a wide array of signaling pathways in the kidney that lead to hypertrophy and matrix expansion, eventually… 
2009
2009
Prostate Cancer Growth Promotes Hormone-Dependent and Hormone-Independent Regulated MicroRNA that − miR-21 : An Androgen Receptor
Androgen receptor (AR)–mediated oncogenic pathways have not been fully elucidated. In this study, we used highthroughput…