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MIR21 gene

Known as: MIR21, MIR-21, hsa-mir-21 
This gene is involved in the regulation of gene expression and plays an oncogenic role in hepatocellular, breast, esophageal, gastric, pancreatic… 
National Institutes of Health

Related topics

Related topics

12 relations
Brainstem gliomaBreast CarcinomaEsophageal carcinomaGlioblastoma

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2014
Highly Cited
2014
Expression of serum miR-16, let-7f, and miR-21 in patients with hepatocellular carcinoma and their clinical significances.
BACKGROUND Recent studies showed that serum microRNAs were aberrantly expressed in cancers, including hepatocellular carcinoma… 
Highly Cited
2014
Highly Cited
2014
High miR‐21 expression from FFPE tissues is associated with poor survival and response to adjuvant chemotherapy in colon cancer
Colon cancer (CC) is a leading cause of cancer mortality. Novel biomarkers are needed to identify CC patients at high risk of… 
Highly Cited
2013
Highly Cited
2013
A new insight into electrochemical microRNA detection: a molecular caliper, p19 protein.
Highly Cited
2013
Highly Cited
2013
miR-21 Down-Regulation Suppresses Cell Growth, Invasion and Induces Cell Apoptosis by Targeting FASL, TIMP3, and RECK Genes in Esophageal Carcinoma
BackgroundmiR-21 is overexpressed in esophageal squamous cell carcinoma (ESCC) and is thought to be correlated with the… 
Highly Cited
2013
Highly Cited
2013
Down-Regulation of PTEN Expression Modulated by Dysregulated miR-21 Contributes to the Progression of Esophageal Cancer
Background and AimmiR-21, a putative tumor oncomiR, is a frequently overexpressed miRNA in a variety of tumors. Because it… 
Highly Cited
2012
Highly Cited
2012
MiR-21 is Continually Elevated Long-Term in the Brain after Exposure to Ionizing Radiation
Ionizing radiation stimulates miR-21 expression in different types of mammalian cells in culture. However, it remains unclear… 
Highly Cited
2011
Highly Cited
2011
Prognostic Significance of miR-181b and miR-21 in Gastric Cancer Patients Treated with S-1/Oxaliplatin or Doxifluridine/Oxaliplatin
Background The goal of this study is to evaluate the effectiveness of S-1/Oxaliplatin vs. Doxifluridine/Oxaliplatin regimen and… 
Highly Cited
2011
Highly Cited
2011
The negative costimulatory molecule PD‐1 modulates the balance between immunity and tolerance via miR‐21
Disruption of the programmed death‐1 (PD‐1) pathway leads to breakdown of peripheral tolerance and initiation of autoimmunity… 
Highly Cited
2010
Highly Cited
2010
Downregulation of miR-21 modulates Ras expression to promote apoptosis and suppress invasion of Laryngeal squamous cell carcinoma.
Highly Cited
2009
Highly Cited
2009
The Modulation of MicroRNAs by Type I IFN through the Activation of Signal Transducers and Activators of Transcription 3 in Human Glioma
Type I IFNs are involved in double-stranded RNA responses. Here, we investigated the possibility that IFN-β may induce or… 
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