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MILR1 gene

Known as: allergy inhibitory receptor 1, mast cell immunoglobulin like receptor 1, MILR1 
 
National Institutes of Health

Papers overview

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2020
2020
Allergin-1 Immunoreceptor Suppresses House Dust Mite–Induced Allergic Airway Inflammation
Key Points Allergin-1 inhibits HDM-induced Syk activation via SHP-1 in CD11b+ DC. Allergin-1 suppresses Th2 response by… Expand
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2019
2019
Selective suppression of oral allergen-induced anaphylaxis by Allergin-1 on basophils in mice.
Mast cells (MCs) play a critical role in oral allergen-induced anaphylaxis. However, the contribution of basophils to the… Expand
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2018
2018
Allergin-1 on mast cells suppresses house dust mite-induced airway hyperresponsiveness in mice
Although airway hyperresponsiveness (AHR) is a prominent feature of asthma, how it is regulated remains incompletely understood… Expand
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2016
2016
Allergin-1 inhibits TLR2-mediated mast cell activation and suppresses dermatitis.
TLR2 recognizes cell wall components of Staphylococcus aureus, which colonizes >90% of atopic eczematous skin lesions. The… Expand
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2014
2014
Influence of MILR1 promoter polymorphism on expression levels and the phenotype of atopy
The recently identified cell surface immunoreceptor MILR1 (mast cell immunoglobulin-like receptor 1; synonyms, Allergin-1) has… Expand
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2013
2013
Expression and Function of Allergin-1 on Human Primary Mast Cells
Mast cells (MC) play an important role in allergic and non-allergic immune responses. Activation of human MC is modulated by… Expand
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2010
2010
An immunoglobulin-like receptor, Allergin-1, inhibits immunoglobulin E–mediated immediate hypersensitivity reactions
Anaphylaxis is a life-threatening immediate hypersensitivity reaction triggered by antigen capture by immunoglobulin E (IgE… Expand
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1995
1995
Identification and characterization of a novel surface antigen gene induced in mast cells activated through the high affinity IgE receptor.
In an effort to isolate novel genes involved in inflammation and/or mast cell activation, we have used a combination of… Expand
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