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MICA wt Allele

Known as: MIC-A, Major Histocompatibility Class I Chain-Related Gene A, PERB11.1 
Human MICA wild-type allele is located in the vicinity of 6p21.3 and is approximately 16 kb in length. This allele, which encodes MHC class I… 
National Institutes of Health

Related topics

Related topics

9 relations
6p21.3Antimicrobial EffectImmune System ProcessesMICA gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Glycogen synthetase kinase 3 inhibition drives MIC‐A/B to promote cytokine production by human natural killer cells in Dengue virus type 2 infection
Dengue virus (DENV) is the most widespread arbovirus worldwide and is responsible for major outbreaks. The host's immune response… 
2003
2003
MIC‐A Genotypes 4/5.1 and 9/9 Are Positively Associated with Type 1 Diabetes Mellitus in Brazilian Population
Abstract: The aim of our study was to evaluate the frequencies of MIC‐A alleles and genotypes in Brazilian patients with type 1… 
2002
2002
MHC Class I Chain‐Related Gene Alleles 5 and 5.1 Are Transmitted More Frequently to Type 1 Diabetes Offspring in HBDI Families
Abstract: Type 1 diabetes mellitus (T1DM) is an autoimmune disease characterized by autoimmune destruction of pancreatic β cells… 
Highly Cited
2002
Highly Cited
2002
Association of the MIC-A gene and HLA-B51 with Behçet's disease in Arabs and non-Ashkenazi Jews in Israel
Background: Behçet's disease is known to be strongly associated with HLA-B51 in many different ethnic groups. Recently, it was… 
2002
2002
Contribution of MIC‐A Polymorphism to Type 1 Diabetes Mellitus in Basques
Abstract: The maximum genetic susceptibility to type 1 diabetes (T1DM) in Basques is conferred by extended HLA haplotype F1C30… 
Highly Cited
2000
Highly Cited
2000
Association of MHC Class I chain-related A (MIC-A) gene polymorphism with Type I diabetes
Aims/hypothesis. A distinct family of MHC genes has been identified in the class III region and denominated MHC Class I chain… 
Highly Cited
1999
Highly Cited
1999
Population study of allelic diversity in the human MHC class I-related MIC-A gene
Abstract The polymorphism of major histocompatibility complex (MHC) class I HLA-A, -B, and -C molecules may have evolved through… 
Highly Cited
1999
Highly Cited
1999
MIC-A polymorphism in Japanese and a MIC-A-MIC-B null haplotype
Abstract A polymorphic gene, MIC-A, is one of the MIC family of genes which is composed of a group of homologous genes… 
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