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MGCD 0103

Known as: MG-0103, MGCD-0103, MGCD0103 
 
National Institutes of Health

Papers overview

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Review
2016
Review
2016
Histone deacetylases (HDACs) are epigenetic regulators that regulate the histone tail, chromatin conformation, protein-DNA… Expand
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2012
2012
BACKGROUND Pancreatic cancer is a highly malignant disease with an extremely poor prognosis. Histone deacetylase inhibitors… Expand
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2011
2011
The chromosomal translocation (8;21) fuses the hematopoietic transcription factor AML1 (RUNX1) with ETO (RUNX1T1, MTG8… Expand
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2010
2010
PURPOSE Single-agent histone deacetylase inhibitors (HDACi) have limited clinical activity in human leukemia. Although the way… Expand
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2009
2009
MGCD0103, an orally available class I histone deacetylase (HDAC) inhibitor, was examined for pre-clinical activity in chronic… Expand
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2009
2009
PURPOSE Histone deacetylase inhibitors have emerged as potent anticancer compounds. Using a nude-mouse xenograft model, for the… Expand
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2009
2009
Unselective histone deacetylase (HDAC) inhibitors are a promising novel therapy for lymphoid malignancies. However, these… Expand
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2009
2009
PURPOSE Investigations of epigenetic drugs have shown that radiotherapy can be successfully combined with histone deacetylase… Expand
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Highly Cited
2008
Highly Cited
2008
The human HDAC (histone deacetylase) family, a well-validated anticancer target, plays a key role in the control of gene… Expand
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Highly Cited
2007
Highly Cited
2007
Advanced second generation inhibitors of histone deacetylases (HDAC) are currently used in clinical development. This study aimed… Expand
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