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MFNG gene

Known as: MFNG, Manic Fringe Homolog (Drosophila) Gene, FRINGE, DROSOPHILA, HOMOLOG OF, MANIC 
This gene plays a role in signal transduction. It is involved in both embryogenesis and morphogenesis.
National Institutes of Health

Related topics

Related topics

4 relations
MFNG protein, humanNeurogenesisPattern FormationSignal Transduction

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Canonical Notch ligands and Fringes have distinct effects on NOTCH1 and NOTCH2
Notch signaling is a cellular pathway regulating cell-fate determination and adult tissue homeostasis. Little is known about how… 
2011
2011
Galactose Differentially Modulates Lunatic and Manic Fringe Effects on Delta1-induced NOTCH Signaling*
Background: The mammalian glycosyltransferases LFNG and MFNG transfer GlcNAc to O-fucose on NOTCH and regulate NOTCH signaling… 
2011
2011
Lunatic Fringe prolongs Delta/Notch-induced self-renewal of committed αβ T-cell progenitors.
Lunatic Fringe (Lfng) enhances Notch1 activation by Delta-like 4 (DL4) to promote Notch1-dependent T-lineage commitment of thymus… 
2009
2009
Differential Axial Requirements for Lunatic Fringe and Hes7 Transcription during Mouse Somitogenesis
Vertebrate segmentation is regulated by the “segmentation clock”, which drives cyclic expression of several genes in the caudal… 
Highly Cited
2008
Highly Cited
2008
Oscillatory lunatic fringe activity is crucial for segmentation of the anterior but not posterior skeleton
The Notch pathway plays multiple roles during vertebrate somitogenesis, functioning in the segmentation clock and during rostral… 
Review
2007
Review
2007
Disruption of the somitic molecular clock causes abnormal vertebral segmentation.
Somites are the precursors of the vertebral column. They segment from the presomitic mesoderm (PSM) that is caudally located and… 
2006
2006
Lunatic Fringe Controls T Cell Differentiation through Modulating Notch Signaling1
T cells differentiate from bone marrow-derived stem cells by expressing developmental stage-specific genes. We here searched… 
Highly Cited
2005
Highly Cited
2005
Role of the hindbrain in dorsoventral but not anteroposterior axial specification of the inner ear
An early and crucial event in vertebrate inner ear development is the acquisition of axial identities that in turn dictate the… 
Highly Cited
2005
Highly Cited
2005
Distinct functional units of the Golgi complex in Drosophila cells.
A striking variety of glycosylation occur in the Golgi complex in a protein-specific manner, but how this diversity and… 
Highly Cited
2002
Highly Cited
2002
Periodic Lunatic fringe expression is controlled during segmentation by a cyclic transcriptional enhancer responsive to notch signaling.
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