METAP2 gene

Known as: METAP2, Peptidase M, p67 
 
National Institutes of Health

Related topics

Related topics

3 relations
METAP1 geneMethionyl Aminopeptidasesmethionine aminopeptidase 2

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2009
Review
2009
Roles of P67/MetAP2 as a tumor suppressor.
A precise balance between growth promoting signals and growth inhibitory signals plays important roles in the maintenance of… (More)
Is this relevant?
2006
2006
A chemical and genetic approach to the mode of action of fumagillin.
Previous mode of action studies identified methionine aminopeptidase 2 (MetAP-2) as the target of the antiangiogenic natural… (More)
Is this relevant?
2006
2006
Microtubule disruption, not calpain-dependent loss of MAP2, contributes to enduring NMDA-induced dendritic dysfunction in acute hippocampal slices
Brief exposure to excitotoxic agonists can result in substantial loss of the microtubule-associated protein MAP2 from neuronal… (More)
Is this relevant?
2004
2004
Partial purification of two proteins (100 kDa and 67 kDa) cooperating in the ATP-dependent inactivation of spinach leaf nitrate reductase
Using a three-step purification procedure, two protein fractions which catalyzed the ATP-dependent in-activation of nitrate… (More)
  • table 1
  • figure 1
  • figure 3
  • figure 2
  • table 2
Is this relevant?
1999
1999
Selective inhibition of amino-terminal methionine processing by TNP-470 and ovalicin in endothelial cells.
BACKGROUND The angiogenesis inhibitors TNP-470 and ovalicin potently suppress endothelial cell growth. Both drugs also… (More)
Is this relevant?
1998
1998
Molecular recognition of angiogenesis inhibitors fumagillin and ovalicin by methionine aminopeptidase 2.
Angiogenesis inhibitors are a novel class of promising therapeutic agents for treating cancer and other human diseases… (More)
  • figure 1
  • table 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
1998
1998
Molecular cloning reveals that the p160 Myb-binding protein is a novel, predominantly nucleolar protein which may play a role in transactivation by Myb.
We have previously detected two related murine nuclear proteins, p160 and p67, that can bind to the leucine zipper motif within… (More)
  • figure 2
  • figure 3
  • figure 4
  • figure 5
  • figure 6
Is this relevant?
1998
1998
Synthetic analogues of TNP-470 and ovalicin reveal a common molecular basis for inhibition of angiogenesis and immunosuppression.
TNP-470 (1), a synthetic derivative of the natural product fumagillin (2), potently inhibits angiogenesis in vivo and the growth… (More)
Is this relevant?
1996
1996
Postsynaptic Mechanisms for Bidirectional Control of MAP2 Phosphorylation by Glutamate Receptors
Many activity-dependent changes in synaptic efficacy occur through elevations in postsynaptic calcium triggered by glutamate… (More)
  • figure 1
  • figure 2
  • figure 5
  • figure 6
  • table 1
Is this relevant?
1996
1996
Emergence of activity-dependent, bidirectional control of microtubule-associated protein MAP2 phosphorylation during postnatal development.
Pronounced changes in neuronal morphology occur as synapses mature; however, little is known about how synaptic transmission… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 5
  • figure 4
Is this relevant?