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METAP2 gene

Known as: METAP2, Peptidase M, p67 
National Institutes of Health

Related topics

Related topics

3 relations
METAP1 geneMethionyl Aminopeptidasesmethionine aminopeptidase 2

Papers overview

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Highly Cited
2005
Highly Cited
2005
Novel inhibitors targeted to methionine aminopeptidase 2 (MetAP2) strongly inhibit the growth of cancers in xenografted nude model
Inhibition of angiogenesis is emerging as a promising strategy for the treatment of cancer. In our study reported here, the… 
Highly Cited
2002
Highly Cited
2002
Methionine Aminopeptidase 2 Is a New Target for the Metastasis-associated Protein, S100A4*
S100A4 is an EF-hand type calcium-binding protein that regulates tumor metastasis and a variety of cellular processes via… 
Highly Cited
1999
Highly Cited
1999
Selective inhibition of amino-terminal methionine processing by TNP-470 and ovalicin in endothelial cells.
Highly Cited
1998
Highly Cited
1998
Molecular recognition of angiogenesis inhibitors fumagillin and ovalicin by methionine aminopeptidase 2.
Angiogenesis inhibitors are a novel class of promising therapeutic agents for treating cancer and other human diseases… 
Highly Cited
1998
Highly Cited
1998
Molecular Cloning Reveals that the p160 Myb-Binding Protein Is a Novel, Predominantly Nucleolar Protein Which May Play a Role in Transactivation by Myb
ABSTRACT We have previously detected two related murine nuclear proteins, p160 and p67, that can bind to the leucine zipper motif… 
Highly Cited
1996
Highly Cited
1996
Postsynaptic Mechanisms for Bidirectional Control of MAP2 Phosphorylation by Glutamate Receptors
Highly Cited
1996
Highly Cited
1996
Emergence of Activity-Dependent, Bidirectional Control of Microtubule-Associated Protein MAP2 Phosphorylation during Postnatal Development
Pronounced changes in neuronal morphology occur as synapses mature; however, little is known about how synaptic transmission… 
Highly Cited
1992
Highly Cited
1992
The eukaryotic initiation factor 2-associated 67-kDa polypeptide (p67) plays a critical role in regulation of protein synthesis initiation in animal cells.
The eukaryotic initiation factor 2 (eIF-2)-associated 67-kDa polypeptide (p67) isolated from reticulocyte lysate protects the eIF… 
Highly Cited
1990
Highly Cited
1990
The phagocyte 47-kilodalton cytosolic oxidase protein is an early reactant in activation of the respiratory burst.
Activation of the phagocyte NADPH oxidase requires participation of membrane-bound cytochrome b558 and cytosol proteins of 47 kDa… 
Highly Cited
1989
Highly Cited
1989
Glycosylation of eukaryotic peptide chain initiation factor 2 (eIF-2)-associated 67-kDa polypeptide (p67) and its possible role in the inhibition of eIF-2 kinase-catalyzed phosphorylation of the eIF…
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