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METAP2 gene

Known as: METAP2, Peptidase M, p67 
National Institutes of Health

Related topics

Related topics

3 relations
METAP1 geneMethionyl Aminopeptidasesmethionine aminopeptidase 2

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2009
Review
2009
Roles of P67/MetAP2 as a tumor suppressor.
  • B. Datta
  • Biochimica et biophysica acta
  • 2009
    • Corpus ID: 22959975
A precise balance between growth promoting signals and growth inhibitory signals plays important roles in the maintenance of… Expand
Highly Cited
2006
Highly Cited
2006
A chemical and genetic approach to the mode of action of fumagillin.
Previous mode of action studies identified methionine aminopeptidase 2 (MetAP-2) as the target of the antiangiogenic natural… Expand
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Highly Cited
1999
Highly Cited
1999
Selective inhibition of amino-terminal methionine processing by TNP-470 and ovalicin in endothelial cells.
BACKGROUND The angiogenesis inhibitors TNP-470 and ovalicin potently suppress endothelial cell growth. Both drugs also… Expand
Highly Cited
1998
Highly Cited
1998
Molecular recognition of angiogenesis inhibitors fumagillin and ovalicin by methionine aminopeptidase 2.
Angiogenesis inhibitors are a novel class of promising therapeutic agents for treating cancer and other human diseases… Expand
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Highly Cited
1998
Highly Cited
1998
Molecular Cloning Reveals that the p160 Myb-Binding Protein Is a Novel, Predominantly Nucleolar Protein Which May Play a Role in Transactivation by Myb
ABSTRACT We have previously detected two related murine nuclear proteins, p160 and p67, that can bind to the leucine zipper motif… Expand
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Highly Cited
1996
Highly Cited
1996
Postsynaptic Mechanisms for Bidirectional Control of MAP2 Phosphorylation by Glutamate Receptors
Many activity-dependent changes in synaptic efficacy occur through elevations in postsynaptic calcium triggered by glutamate… Expand
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Highly Cited
1996
Highly Cited
1996
Emergence of Activity-Dependent, Bidirectional Control of Microtubule-Associated Protein MAP2 Phosphorylation during Postnatal Development
Pronounced changes in neuronal morphology occur as synapses mature; however, little is known about how synaptic transmission… Expand
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Highly Cited
1992
Highly Cited
1992
The eukaryotic initiation factor 2-associated 67-kDa polypeptide (p67) plays a critical role in regulation of protein synthesis initiation in animal cells.
The eukaryotic initiation factor 2 (eIF-2)-associated 67-kDa polypeptide (p67) isolated from reticulocyte lysate protects the eIF… Expand
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Highly Cited
1990
Highly Cited
1990
The phagocyte 47-kilodalton cytosolic oxidase protein is an early reactant in activation of the respiratory burst.
Activation of the phagocyte NADPH oxidase requires participation of membrane-bound cytochrome b558 and cytosol proteins of 47 kDa… Expand
Highly Cited
1989
Highly Cited
1989
Glycosylation of eukaryotic peptide chain initiation factor 2 (eIF-2)-associated 67-kDa polypeptide (p67) and its possible role in the inhibition of eIF-2 kinase-catalyzed phosphorylation of the eIF…
We have reported previously that a 67-kDa polypeptide (p67) present in reticulocyte lysates protects the alpha-subunit of… Expand
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