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MEI4 gene

Known as: MEI4, meiotic double-stranded break formation protein 4 
 
National Institutes of Health

Papers overview

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2018
2018
Mouse REC114 is essential for meiotic DNA double-strand break formation and forms a complex with MEI4
Mouse REC114 is essential for meiotic DNA double-strand break formation and forms a complex with IHO1. Its N-terminal region… Expand
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2015
2015
MEI4 – a central player in the regulation of meiotic DNA double‐strand break formation in the mouse
The formation of programmed DNA double‐strand breaks (DSBs) at the beginning of meiotic prophase marks the initiation of meiotic… Expand
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Highly Cited
2011
Highly Cited
2011
Spo11-Accessory Proteins Link Double-Strand Break Sites to the Chromosome Axis in Early Meiotic Recombination
Meiotic recombination between homologous chromosomes initiates via programmed DNA double-strand breaks (DSBs), generated by… Expand
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Highly Cited
2010
Highly Cited
2010
Functional conservation of Mei4 for meiotic DNA double-strand break formation from yeasts to mice.
Meiotic recombination is initiated by the programmed induction of DNA double-strand breaks (DSBs) catalyzed by the evolutionarily… Expand
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Highly Cited
2008
Highly Cited
2008
Cdc7-dependent phosphorylation of Mer2 facilitates initiation of yeast meiotic recombination.
Meiosis ensures genetic diversification of gametes and sexual reproduction. For successful meiosis, multiple events such as DNA… Expand
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Highly Cited
2007
Highly Cited
2007
Interactions between Mei4, Rec114, and other proteins required for meiotic DNA double-strand break formation in Saccharomyces cerevisiae
In most sexually reproducing organisms, meiotic recombination is initiated by DNA double-strand breaks (DSBs) formed by the Spo11… Expand
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Highly Cited
2006
Highly Cited
2006
Saccharomyces cerevisiae Mer2, Mei4 and Rec114 Form a Complex Required for Meiotic Double-Strand Break Formation
In budding yeast, at least 10 proteins are required for formation of the double-strand breaks (DSBs) that initiate meiotic… Expand
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2001
2001
Counteracting regulation of chromatin remodeling at a fission yeast cAMP response element-related recombination hotspot by stress-activated protein kinase, cAMP-dependent kinase and meiosis…
In fission yeast, an ATF/CREB-family transcription factor Atf1-Pcr1 plays important roles in the activation of early meiotic… Expand
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Highly Cited
2000
Highly Cited
2000
Autoregulated expression of Schizosaccharomyces pombe meiosis-specific transcription factor Mei4 and a genome-wide search for its target genes.
The Schizosaccharomyces pombe mei4(+) gene encoding a forkhead transcription factor is necessary for the progression of meiosis… Expand
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Highly Cited
1998
Highly Cited
1998
The Schizosaccharomyces pombe mei4+ gene encodes a meiosis-specific transcription factor containing a forkhead DNA-binding domain.
The mei4+ gene of the fission yeast Schizosaccharomyces pombe was cloned by functional complementation. The mei4 disruptant… Expand
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