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MDL 28170

Known as: MDL-28170, MDL28170 
 
National Institutes of Health

Papers overview

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2012
2012
P2X7 receptor (P2X7R) is known to be a 'death receptor' in immune cells, but its functional expression in non-immune cells such… Expand
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Highly Cited
2012
Highly Cited
2012
The K-Cl cotransporter KCC2 plays a crucial role in neuronal chloride regulation. In mature central neurons, KCC2 is responsible… Expand
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2011
2011
BACKGROUND Trypanosoma cruzi is the etiological agent of Chagas' disease. During the parasite life cycle, many molecules are… Expand
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2009
2009
Cyclin-dependent kinase 5 (Cdk5) is a serine-threonine kinase important for different cellular processes. Involved in tau protein… Expand
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2008
2008
Neurodegeneration induced by the NMDA receptor antagonist, phencyclidine (PCP), has been used to model the pathogenesis of… Expand
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2006
2006
Abstract Several calpain inhibitors are under development and some are useful agents against important human pathogens. We… Expand
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2005
2005
MDL 28170 is a CNS-penetrating calpain inhibitor, and we examined the effects of MDL 28170 on hypoxic-ischemic brain injury in… Expand
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2004
2004
Oxygen-glucose deprivation (OGD) induced neuron-specific cell death in organotypic hippocampal slice cultures. Neuronal death was… Expand
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Highly Cited
2003
Highly Cited
2003
Traumatic brain injury (TBI) evokes diffuse (traumatic) axonal injury (TAI), which contributes to morbidity and mortality… Expand
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1998
1998
The newly-developed calpain inhibitor, MDL 28170 penetrates the blood-brain barrier and inhibits brain cysteine protease activity… Expand
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