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MB21D1 protein, human

Known as: cGAS protein, human, MB21D1, EC 2.7.7.- 
Cyclic GMP-AMP synthase (522 aa, ~59 kDa) is encoded by the human MB21D1 gene. This protein plays a role both cyclic dinucleotide synthesis and… 
National Institutes of Health

Related topics

Related topics

9 relations
Cytoplasmic matrixEnzyme GeneImmunityMB21D1 gene

Broader (1)

nucleotidyltransferase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2020
Review
2020
Conserved strategies for pathogen evasion of cGAS–STING immunity
Highly Cited
2017
Highly Cited
2017
Psychiatric Disorders in Adolescents With Single Ventricle Congenital Heart Disease
Examination of adolescents with critical congenital heart disease revealed high risk for certain psychiatric morbidities… 
Highly Cited
2017
Highly Cited
2017
miR25/93 mediates hypoxia-induced immunosuppression by repressing cGAS
The mechanisms by which hypoxic tumours evade immunological pressure and anti-tumour immunity remain elusive. Here, we report… 
Highly Cited
2014
Highly Cited
2014
Polymer/graphene hybrid aerogel with high compressibility, conductivity, and "sticky" superhydrophobicity.
The idea of extending functions of graphene aerogels and achieving specific applications has aroused wide attention recently. A… 
Highly Cited
2010
Highly Cited
2010
Measurement of caffeic and ferulic acid equivalents in plasma after coffee consumption: small intestine and colon are key sites for coffee metabolism.
Previous studies on coffee examined absorption of phenolic acids (PA) in the small intestine, but not the contribution of the… 
Highly Cited
2010
Highly Cited
2010
The effectiveness of a comprehensive geriatric assessment intervention program for frailty in community-dwelling older people: a randomized, controlled trial.
Highly Cited
2010
Highly Cited
2010
Biochemical and molecular characterization of the antioxidative system of Coffea sp. under cold conditions in genotypes with contrasting tolerance.
Highly Cited
2003
Highly Cited
2003
Ages of onset and rates of syndromal and subsyndromal comorbid DSM-IV diagnoses in a prepubertal and early adolescent bipolar disorder phenotype.
OBJECTIVE To study rates and ages of onset of DSM-IV syndromal and subsyndromal comorbidity in a prepubertal and early adolescent… 
Highly Cited
1997
Highly Cited
1997
Child and adolescent obsessive-compulsive disorder treated with citalopram: findings from an open trial of 23 cases.
The adverse effects and potential clinical value of citalopram, a highly selective serotonin reuptake inhibitor, were examined in… 
Highly Cited
1995
Highly Cited
1995
Inter-rater reliability of global assessment of functioning in a clinical setting.
Four studies on the inter-rater reliability of a proposed Axis V version for DSM-IV and of the CGAS involving 162 child and… 
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