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MARK4 gene

Known as: MAP/Microtubule Affinity-Regulating Kinase 4 Gene, MARK4, Nbla00650 
This gene plays a role in protein phosphorylation.
National Institutes of Health

Related topics

Related topics

5 relations
Microtubule ProcessPhosphorylationSerine/Threonine PhosphorylationSignal Transduction

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
MARK2 inhibits the growth of HeLa cells through AMPK and reverses epithelial-mesenchymal transition.
Microtubule affinity-regulating kinases (MARKs; MARK1, MARK2, MARK3 and MARK4) act directly downstream of LKB1, the multitasking… 
2015
2015
Designing New Kinase Inhibitor Derivatives as Therapeutics Against Common Complex Diseases: Structural Basis of Microtubule Affinity-Regulating Kinase 4 (MARK4) Inhibition.
Drug development for common complex diseases is in need of new molecular entities and actionable drug targets. MAP/microtubule… 
2015
2015
Crystal structure of microtubule affinity-regulating kinase 4 catalytic domain in complex with a pyrazolopyrimidine inhibitor.
Microtubule-associated protein/microtubule affinity-regulating kinase 4 (MARK4) is a serine/threonine kinase involved in the… 
2014
2014
Microtubule-associated protein/microtubule affinity-regulating kinase 4 (MARK4) plays a role in cell cycle progression and cytoskeletal dynamics.
2014
2014
Cloning, Expression, Purification and Refolding of Microtubule Affinity-Regulating Kinase 4 Expressed in Escherichia coli
Microtubule-associated protein/microtubule affinity-regulating kinase 4 (MARK4) is a member of the family Ser/Thr kinase and… 
2012
2012
Secretome analysis of ionizing radiation‐induced senescent cancer cells reveals that secreted RKIP plays a critical role in neighboring cell migration
Cellular senescence is a physiological program of irreversible growth arrest that is considered to play an important role in… 
2012
2012
Reduction of protein kinase MARK4 in the brains of experimental scrapie rodents and human prion disease correlates with deposits of PrP(Sc).
Microtubule affinity-regulating kinase 4 (MARK4) belongs to a family of kinases that are able to actively phosphorylate the… 
2009
2009
Hunting for the SNARK in metabolic disease.
dysregulation of energy balance is a primary constituent in the etiology of obesity and type 2 diabetes mellitus, which is… 
2009
2009
Multiple Localization of Endogenous MARK4L Protein in Human Glioma
Background: We have previously shown that the sustained expression of MARK4L transcripts in glioma and neural progenitors (NHNPs… 
2008
2008
Regulation of the AMPK-related protein kinases by ubiquitination.
How can a constitutively active 'master' kinase with numerous downstream targets preferentially phosphorylate one or more of… 
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