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MARK2 wt Allele

Known as: EMK-1, PAR-1, Par1b 
Human MARK2 wild-type allele is located in the vicinity of 11q13.1 and is approximately 72 kb in length. This allele, which encodes serine/threonine… 
National Institutes of Health

Related topics

Related topics

7 relations
11q13.1MARK2 geneMARK2 protein, humanMicrotubule Process

Papers overview

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Highly Cited
2012
Highly Cited
2012
Phospho-dependent ubiquitination and degradation of PAR-1 regulates synaptic morphology and tau-mediated Aβ toxicity in Drosophila
The conserved kinases PAR-1/MARK are critically involved in processes such as asymmetric cell division, cell polarity and… 
Highly Cited
2009
Highly Cited
2009
PP2A antagonizes phosphorylation of Bazooka by PAR-1 to control apical-basal polarity in dividing embryonic neuroblasts.
Highly Cited
2009
Highly Cited
2009
PAR-1 phosphorylates Mind bomb to promote vertebrate neurogenesis.
Highly Cited
2007
Highly Cited
2007
PAR-1 Kinase Phosphorylates Dlg and Regulates Its Postsynaptic Targeting at the Drosophila Neuromuscular Junction
Highly Cited
2005
Highly Cited
2005
PAR-1 Activation on Human Late Endothelial Progenitor Cells Enhances Angiogenesis In Vitro With Upregulation of the SDF-1/CXCR4 System
Objectives—The importance of PAR-1 in blood vessel development has been demonstrated in knockout mice. As endothelial progenitor… 
Highly Cited
2005
Highly Cited
2005
Distinct PAR-1 proteins function in different branches of Wnt signaling during vertebrate development.
Highly Cited
2004
Highly Cited
2004
Modulation of KSR activity in Caenorhabditis elegans by Zn ions, PAR‐1 kinase and PP2A phosphatase
Vulval differentiation in Caenorhabditis elegans is controlled by a conserved signal transduction pathway mediated by Ras and a… 
Highly Cited
2002
Highly Cited
2002
Drosophila 14-3-3/PAR-5 is an essential mediator of PAR-1 function in axis formation.
Highly Cited
2002
Highly Cited
2002
Par-1 regulates stability of the posterior determinant Oskar by phosphorylation
Par-1 kinase is critical for polarization of the Drosophila melanogaster oocyte and the one-cell Caenorhabditis elegans embryo… 
Highly Cited
1999
Highly Cited
1999
Thrombin and mast cell tryptase regulate guinea‐pig myenteric neurons through proteinase‐activated receptors‐1 and −2
1 Proteases regulate cells by cleaving proteinase‐activated receptors (PARs). Thrombin and trypsin cleave PAR‐1 and PAR‐2 on… 
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