MARK2 wt Allele

Known as: EMK-1, PAR-1, Par1b 
Human MARK2 wild-type allele is located in the vicinity of 11q13.1 and is approximately 72 kb in length. This allele, which encodes serine/threonine… (More)
National Institutes of Health

Papers overview

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2012
2012
The conserved kinases PAR-1/MARK are critically involved in processes such as asymmetric cell division, cell polarity and… (More)
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2007
2007
Targeting of synaptic molecules to their proper location is essential for synaptic differentiation and plasticity. PSD-95/Dlg… (More)
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Highly Cited
2005
Highly Cited
2005
The kinase PAR-1 plays conserved roles in cell polarity. PAR-1 has also been implicated in axis establishment in C. elegans and… (More)
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Highly Cited
2005
Highly Cited
2005
OBJECTIVE The importance of PAR-1 in blood vessel development has been demonstrated in knockout mice. As endothelial progenitor… (More)
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Highly Cited
2004
Highly Cited
2004
Multisite hyperphosphorylation of tau has been implicated in the pathogenesis of neurodegenerative diseases including Alzheimer's… (More)
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Highly Cited
2002
Highly Cited
2002
PAR-1 kinases are required to determine the anterior-posterior (A-P) axis in C. elegans and Drosophila, but little is known about… (More)
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2002
2002
Par-1 kinase is critical for polarization of the Drosophila melanogaster oocyte and the one-cell Caenorhabditis elegans embryo… (More)
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Highly Cited
2001
Highly Cited
2001
We utilized a cDNA expression library derived from the B6SutA1 mouse myeloid progenitor cell line to search for novel oncogenes… (More)
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Highly Cited
1999
Highly Cited
1999
We developed mice deficient in protease-activated receptor-2 (PAR-2) or PAR-1 to explore the pathophysiological functions of… (More)
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Highly Cited
1999
Highly Cited
1999
1. Proteases regulate cells by cleaving proteinase-activated receptors (PARs). Thrombin and trypsin cleave PAR-1 and PAR-2 on… (More)
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