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MARK2 wt Allele

Known as: EMK-1, PAR-1, Par1b 
Human MARK2 wild-type allele is located in the vicinity of 11q13.1 and is approximately 72 kb in length. This allele, which encodes serine/threonine… Expand
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
Bazooka/Par-3 (Baz) is a key regulator of cell polarity in epithelial cells and neuroblasts (NBs). Phosphorylation of Baz by PAR… Expand
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Highly Cited
2007
Highly Cited
2007
Targeting of synaptic molecules to their proper location is essential for synaptic differentiation and plasticity. PSD-95/Dlg… Expand
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Highly Cited
2005
Highly Cited
2005
Objectives—The importance of PAR-1 in blood vessel development has been demonstrated in knockout mice. As endothelial progenitor… Expand
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Highly Cited
2005
Highly Cited
2005
The kinase PAR-1 plays conserved roles in cell polarity. PAR-1 has also been implicated in axis establishment in C. elegans and… Expand
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Highly Cited
2004
Highly Cited
2004
Multisite hyperphosphorylation of tau has been implicated in the pathogenesis of neurodegenerative diseases including Alzheimer's… Expand
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Highly Cited
2002
Highly Cited
2002
PAR-1 kinases are required to determine the anterior-posterior (A-P) axis in C. elegans and Drosophila, but little is known about… Expand
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Highly Cited
2001
Highly Cited
2001
Wnt signalling regulates β-catenin-dependent developmental processes through the Dishevelled protein (Dsh). Dsh regulates two… Expand
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Highly Cited
2001
Highly Cited
2001
We utilized a cDNA expression library derived from the B6SutA1 mouse myeloid progenitor cell line to search for novel oncogenes… Expand
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Highly Cited
1999
Highly Cited
1999
We developed mice deficient in protease-activated receptor-2 (PAR-2) or PAR-1 to explore the pathophysiological functions of… Expand
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Highly Cited
1999
Highly Cited
1999
1 Proteases regulate cells by cleaving proteinase‐activated receptors (PARs). Thrombin and trypsin cleave PAR‐1 and PAR‐2 on… Expand
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