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MARCH5 gene

Known as: FLJ20445, MARCH-V, MARCH V 
National Institutes of Health

Related topics

Related topics

1 relation
MARCH2 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
MARCH5 mediates NOXA-dependent MCL1 degradation driven by kinase inhibitors and integrated stress response activation
MCL1 has critical antiapoptotic functions and its levels are tightly regulated by ubiquitylation and degradation, but mechanisms… 
Highly Cited
2019
Highly Cited
2019
MITOL prevents ER stress‐induced apoptosis by IRE1α ubiquitylation at ER–mitochondria contact sites
Unresolved endoplasmic reticulum (ER) stress shifts the unfolded protein response signaling from cell survival to cell death… 
Highly Cited
2017
Highly Cited
2017
Mitochondrial E3 ligase MARCH5 regulates FUNDC1 to fine‐tune hypoxic mitophagy
Mitophagy is an essential process for mitochondrial quality control and turnover. It is activated by two distinct pathways, one… 
Review
2017
Review
2017
Mitochondrial Control of Innate Immunity and Inflammation
Mitochondria are key organelles involved in energy production, functioning as the metabolic hubs of cells. Recent findings… 
Highly Cited
2017
Highly Cited
2017
Novel regulatory roles of Mff and Drp1 in E3 ubiquitin ligase MARCH5–dependent degradation of MiD49 and Mcl1 and control of mitochondrial dynamics
In addition to their direct roles in mitochondrial fission, Mff and Drp1 act as regulatory factors and control mitochondrial… 
Highly Cited
2016
Highly Cited
2016
Mitochondrial E3 ubiquitin ligase MARCH5 controls mitochondrial fission and cell sensitivity to stress-induced apoptosis through regulation of MiD49 protein
The data presented support a critical role for MARCH5 in the regulation of mitochondrial fission and cell viability. Through… 
Highly Cited
2015
Highly Cited
2015
The mitochondrial ubiquitin ligase MARCH5 resolves MAVS aggregates during antiviral signalling
Mitochondria serve as platforms for innate immunity. The mitochondrial antiviral signalling (MAVS) protein forms aggregates that… 
Highly Cited
2014
Highly Cited
2014
MARCH5-mediated quality control on acetylated Mfn1 facilitates mitochondrial homeostasis and cell survival
Mitochondrial dynamics and quality control have a central role in the maintenance of cellular integrity. Mitochondrial ubiquitin… 
2014
2014
Mitochondrial hyperfusion promotes NF‐κB activation via the mitochondrial E3 ligase MULAN
Mitochondria are dynamic organelles with a morphology resulting from the balance between two opposing processes: fusion and… 
Highly Cited
2012
Highly Cited
2012
Mitofusin 1 is degraded at G2/M phase through ubiquitylation by MARCH5
BackgroundMitochondria exhibit a dynamic morphology in cells and their biogenesis and function are integrated with the nuclear… 
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