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MAP2K2 protein, human

Known as: ERK Activator Kinase 2, MEK 2, mitogen-activated protein kinase kinase 2, human 
Dual specificity mitogen-activated protein kinase kinase 2 (400 aa, ~44 kDa) is encoded by the human MAP2K2 gene. This protein plays a role in… Expand
National Institutes of Health

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Angiotensin II Signaling PathwayB Cell Receptor Signaling PathwayCalpain-2 Cell Motility PathwayCardiac Hypertrophy Pathway
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MAP Kinase Kinase 2

Papers overview

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2017
2017
Phosphoproteome-based kinase activity profiling reveals the critical role of MAP2K2 and PLK1 in neuronal autophagy
ABSTRACTRecent studies have demonstrated that dysregulation of macroautophagy/autophagy may play a central role in the… Expand
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2017
2017
Phosphoproteome-based kinase activity profiling reveals the critical role of MAP2K2 and PLK1 in neuronal autophagy.
Recent studies have demonstrated that dysregulation of macroautophagy/autophagy may play a central role in the pathogenesis of… Expand
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2017
2017
p53 regulates ERK1/2/CREB cascade via a novel SASH1/MAP2K2 crosstalk to induce hyperpigmentation
We previously reported that three point mutations in SASH1 and mutated SASH1 promote melanocyte migration in dyschromatosis… Expand
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2016
2016
Identification of a RAI1-associated disease network through integration of exome sequencing, transcriptomics, and 3D genomics
BackgroundSmith-Magenis syndrome (SMS) is a developmental disability/multiple congenital anomaly disorder resulting from… Expand
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2013
2013
Multiple myeloma is affected by multiple and heterogeneous somatic mutations in adhesion- and receptor tyrosine kinase signaling molecules
Multiple myeloma (MM) is a largely incurable plasma cell malignancy with a poorly understood and heterogeneous clinical course… Expand
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