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MAP2K2 gene

Known as: Mitogen-Activated Protein Kinase Kinase 2 Gene, MKK2, PRKMK2 
This gene plays a role in both protein phosphorylation and signal transduction.
National Institutes of Health

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7 relations
Intracellular TransportMAP Kinase Kinase 2MAP2K2 protein, humanPhosphorylation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Sequential treatment failures in response to BRAF/MEK and immune checkpoint inhibitors mediated by MAP2K2 and B2M mutations in melanoma.
2017
2017
Comparative Phosphoproteomics Reveals an Important Role of MKK2 in Banana (Musa spp.) Cold Signal Network
Low temperature is one of the key environmental stresses, which greatly affects global banana production. However, little is… 
2017
2017
Upregulated expression of MMP-9 in gingival epithelial cells induced by prolonged stimulation with arecoline.
Betel quid chewing is implicated in the high prevalence of oral cancer in Southeast Asian countries. One of the major components… 
2016
2016
Concurrent occurrence of an inherited 16p13.11 microduplication and a de novo 19p13.3 microdeletion involving MAP2K2 in a patient with developmental delay, distinctive facial features, and lambdoid…
Review
2014
Review
2014
Multiple café au lait spots in familial patients with MAP2K2 mutation
Recent advances in genetic diagnostic technologies have made the classic disease nosology highly complicated. This situation is… 
2003
2003
An enzymatic electrochemiluminescence assay for the lethal factor of anthrax.
2000
2000
Chromosome mapping of the human genes encoding the MAP kinase kinase MEK1 (MAP2K1) to 15q21 and MEK2 (MAP2K2) to 7q32
Activation of the ERK mitogen-activated protein (MAP) kinase pathway has been implicated in the regulation of cell growth… 
Highly Cited
1996
Highly Cited
1996
Constitutively active mitogen-activated protein kinase kinase 1 (MAPKK1) and MAPKK2 mediate similar transcriptional and morphological responses.
Both mitogen-activated protein kinase kinase 1 (MAPKK1) and MAPKK2 function downstream of the proto-oncogene product Raf in… 
1995
1995
Activation of two isoforms of mitogen-activated protein kinase kinase in response to epidermal growth factor and nerve growth factor.
Mitogen-activated protein kinase kinase (MAPKK) is a dual-specificity protein kinase which phosphorylates and activates mitogen… 
1994
1994
The threonine residues in MAP kinase kinase 1 phosphorylated by MAP kinase in vitro are also phosphorylated in nerve growth factor‐stimulated rat phaeochromocytoma (PC12) cells
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