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MAP Kinase Kinase 6

Known as: Stress-Activated Protein Kinase Kinase-3, Mitogen Activated Protein Kinase Kinase 6, Protein Kinase, SAPKK3 
A mitogen-activated protein kinase kinase with specificity for P38 MITOGEN-ACTIVATED PROTEIN KINASES.
National Institutes of Health

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In BloodMAP2K6 geneProcess of secretionantagonists & inhibitors

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MAP2K6 protein, human

Papers overview

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2020
2020
Optical control of MAP kinase kinase 6 (MKK6) reveals that it has divergent roles in pro-apoptotic and anti-proliferative signaling
The selective pressure imposed by extrinsic death signals and stressors adds to the challenge of isolating and interpreting the… 
2018
2018
Protective effect of coptisine free base on indomethacin‐induced gastric ulcers in rats: Characterization of potential molecular mechanisms
2017
2017
Identification of growth trait related genes in a Yorkshire purebred pig population by genome-wide association studies
Objective The aim of this study is to identify genomic regions or genes controlling growth traits in pigs. Methods Using a panel… 
2014
2014
Genome-wide transcriptome modulation in rice transgenic lines expressing engineered mitogen activated protein kinase kinase 6
Mitogen activated protein kinase kinase (MAPKK) is the central module of MAPK cascade and also point of signal integration and… 
Highly Cited
2013
Highly Cited
2013
Overexpression of constitutively active mitogen activated protein kinase kinase 6 enhances tolerance to salt stress in rice
BackgroundSalinity is one of the most common abiotic stresses encountered by plants in the environment and transgenic approaches… 
2012
2012
Involvement of mitogen activated protein kinase kinase 6 in UV induced transcripts accumulation of genes in phytoalexin biosynthesis in rice
BackgroundUltra violet radiation leads to accumulation of phytoalexins (PA) in rice (Oryza sativa) which are typically… 
2008
2008
Atlantic salmon possess three mitogen activated protein kinase kinase 6 paralogs responding differently to stress
Mitogen activated protein kinase kinase (MKK) 3 and 6 are the main p38 mitogen‐activated protein kinase activators in mammals. In… 
Highly Cited
2005
Highly Cited
2005
Activation of p21-activated Kinase 6 by MAP Kinase Kinase 6 and p38 MAP Kinase*
The p21-activated kinases (PAKs) contain an N-terminal Cdc42/Rac interactive binding domain, which in the group 1 PAKs (PAK1, 2… 
2005
2005
Activation of Mitogen-activated Protein Kinase Kinase (MKK) 3 and MKK6 by Type I Interferons*
There is accumulating evidence that the p38 MAP kinase pathway plays important roles in Type I interferon (IFN) signaling, but… 
Highly Cited
1996
Highly Cited
1996
Characterization of the Structure and Function of a New Mitogen-activated Protein Kinase (p38β)*
Mitogen-activated protein (MAP) kinase cascades represent one of the major signal systems used by eukaryotic cells to transduce… 
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