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MAP Kinase Kinase 6

Known as: Stress-Activated Protein Kinase Kinase-3, Mitogen Activated Protein Kinase Kinase 6, Protein Kinase, SAPKK3 
A mitogen-activated protein kinase kinase with specificity for P38 MITOGEN-ACTIVATED PROTEIN KINASES.
National Institutes of Health

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In BloodMAP2K6 geneProcess of secretionantagonists & inhibitors

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MAP2K6 protein, human

Papers overview

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2020
2020
Optical control of MAP kinase kinase 6 (MKK6) reveals that it has divergent roles in pro-apoptotic and anti-proliferative signaling
The selective pressure imposed by extrinsic death signals and stressors adds to the challenge of isolating and interpreting the… 
2014
2014
Genome-wide transcriptome modulation in rice transgenic lines expressing engineered mitogen activated protein kinase kinase 6
Mitogen activated protein kinase kinase (MAPKK) is the central module of MAPK cascade and also point of signal integration and… 
Highly Cited
2013
Highly Cited
2013
Overexpression of constitutively active mitogen activated protein kinase kinase 6 enhances tolerance to salt stress in rice
Salinity is one of the most common abiotic stresses encountered by plants in the environment and transgenic approaches offer new… 
2013
2013
Involvement of mitogen activated protein kinase kinase 6 in UV induced transcripts accumulation of genes in phytoalexin biosynthesis in rice
Ultra violet radiation leads to accumulation of phytoalexins (PA) in rice (Oryza sativa) which are typically accumulated when the… 
2008
2008
Atlantic salmon possess three mitogen activated protein kinase kinase 6 paralogs responding differently to stress
Mitogen activated protein kinase kinase (MKK) 3 and 6 are the main p38 mitogen‐activated protein kinase activators in mammals. In… 
2006
2006
Nuclear protein NP60 regulates p38 MAPK activity
The activation of p38α is mediated by its upstream kinase and associated proteins. Here we identify a new nuclear protein, NP60… 
Highly Cited
2005
Highly Cited
2005
Activation of p21-activated Kinase 6 by MAP Kinase Kinase 6 and p38 MAP Kinase*
The p21-activated kinases (PAKs) contain an N-terminal Cdc42/Rac interactive binding domain, which in the group 1 PAKs (PAK1, 2… 
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