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MAGEC2 wt Allele

Known as: HCA587, CT10, MAGEE1 
Human MAGEC2 wild-type allele is located in the vicinity of Xq27 and is approximately 3 kb in length. This allele, which encodes melanoma-associated… 
National Institutes of Health

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Immune response

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
HCA587 protein vaccine induces specific antitumor immunity mediated by CD4+ T-cells expressing granzyme B in a mouse model of melanoma.
BACKGROUND The antigen HCA587 (also known as MAGE-C2), which is considered a cancer-testis antigen, exhibits upregulated… 
2019
2019
Evaluation of cancer testis antigen (CT10, PRAME) and MHC I expression in high grade urothelial carcinoma of the bladder
Immunotherapeutic strategies are increasingly used in the treatment of a number of malignancies including high-grade urothelial… 
2015
2015
Intratumoral Heterogeneity of MAGE-C1/CT7 and MAGE-C2/CT10 Expression in Mucosal Melanoma
Mucosal melanoma is a rare disease, which differs from its cutaneous counterpart genetically and for its clinical behaviour… 
2014
2014
The rate and pattern of urea infusion into the rumen of wethers alters nitrogen balance and plasma ammonia.
Changes in N balance, urinary excretion of purine derivative (PD), urea, creatinine and ammonia and plasma ammonia, glucose, urea… 
2013
2013
Heterogeneous expression of CT10, CT45 and GAGE7 antigens and their prognostic significance in human breast carcinoma.
OBJECTIVE The goal of this study was to detect the intertumoral heterogeneity of CT10, CT45 and GAGE7 expression and further to… 
2010
2010
A complex RNA-cleaving DNAzyme that can efficiently cleave a pyrimidine-pyrimidine junction.
2005
2005
[The expression of 11 cancer/testis (CT) antigen genes in esophageal carcinoma].
OBJECTIVE To investigate the expression status of 11 different cancer/testis (CT) antigen genes in esophageal carcinoma… 
2004
2004
Elicitation of Both CD4+ and CD8+ T‐Cell‐Mediated Specific Immune Responses to HCA587 Protein by Autologous Dendritic Cells
We recently cloned a new member of cancer/testis antigen named HCA587, which was highly expressed in human hepatocellular… 
2003
2003
Expression, purification and serological analysis of hepatocellular carcinoma associated antigen HCA587 in insect cells.
AIM In order to assess hepatocellular carcinoma associated antigen HCA587 as a potential target for immunotherapy, the Bac-to-Bac… 
2000
2000
Gure, A. O. et al. CT10: a new cancer-testis (CT) antigen homologous to CT7 and the MAGE family, identified by representational-difference analysis. Int. J. Cancer 85, 726-732
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