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MAFA gene

Known as: V-MAF AVIAN MUSCULOAPONEUROTIC FIBROSARCOMA ONCOGENE HOMOLOG A, RIPE3b1, hMafA 
This gene plays a role in the regulation of insulin gene expression.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Pancreatic β-cell-restricted expression of insulin is established through several critical cis-regulatory elements located in the… Expand
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2007
2007
Transcription factors, such as PDX-1, that normally mediate pancreatic development are capable of inducing hepatic progenitor… Expand
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Highly Cited
2006
Highly Cited
2006
Major insulin gene transcription factors, such as PDX-1 or NeuroD1, have equally important roles in pancreatic development and… Expand
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Highly Cited
2002
Highly Cited
2002
Of the three critical enhancer elements that mediate beta-cell-specific and glucose-responsive expression of the insulin gene… Expand
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2001
2001
Transcription factors binding the insulin enhancer region, RIPE3b, mediate beta-cell type-specific and glucose-responsive… Expand
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2001
2001
The RIPE3b1 DNA binding factor plays a critical role in pancreatic islet beta cell-specific and glucose-regulated transcription… Expand
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2000
2000
Glucose-stimulated and pancreatic islet beta cell-specific expression of the insulin gene is mediated in part by the C1 DNA… Expand
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Highly Cited
1996
Highly Cited
1996
We have shown previously that chronic exposure of HIT-T15 cells to supraphysiologic glucose concentrations causes decreased… Expand
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Highly Cited
1995
Highly Cited
1995
The most important regulator of insulin gene expression in pancreatic beta- cells is glucose, which affects gene transcription… Expand
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1994
1994
The insulin gene is expressed exclusively in pancreatic islet beta cells. The principal regulator of insulin gene transcription… Expand
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