FAQ

MAFA gene

Known as: V-MAF AVIAN MUSCULOAPONEUROTIC FIBROSARCOMA ONCOGENE HOMOLOG A, hMafA, MAFA 
This gene plays a role in the regulation of insulin gene expression.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1994-2017
0119942017

Related topics

Related topics

4 relations
Homo sapiensMAFA protein, humanTranscriptional Regulationdna binding

Related mentions per year

Related mentions per year

1937-2018
19401960198020002020
MAFA gene
Transcriptional Regulation
dna binding
Homo sapiens
MAFA protein, human

Papers overview

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2013
2013
Comprehensive identification of high-frequency and co-occurring Mafa-DPA1, Mafa-DQA1, Mafa-DRA, and Mafa-DOA alleles in Vietnamese cynomolgus macaques
High-frequency alleles and/or co-occurring human leukocyte antigen alleles across loci appear to be more important than… (More)
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2007
2007
Islet cell differentiation in liver by combinatorial expression of transcription factors neurogenin-3, BETA2, and RIPE3b1.
Transcription factors, such as PDX-1, that normally mediate pancreatic development are capable of inducing hepatic progenitor… (More)
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2003
2003
The islet beta cell-enriched RIPE3b1/Maf transcription factor regulates pdx-1 expression.
Pancreatic duodenal homeobox factor-1, PDX-1, is required for pancreas development, islet cell differentiation, and the… (More)
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Highly Cited
2002
Highly Cited
2002
Identification of beta-cell-specific insulin gene transcription factor RIPE3b1 as mammalian MafA.
Of the three critical enhancer elements that mediate beta-cell-specific and glucose-responsive expression of the insulin gene… (More)
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2001
2001
Transcription factors recognizing overlapping C1-A2 binding sites positively regulate insulin gene expression.
Transcription factors binding the insulin enhancer region, RIPE3b, mediate beta-cell type-specific and glucose-responsive… (More)
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2001
2001
The DNA binding activity of the RIPE3b1 transcription factor of insulin appears to be influenced by tyrosine phosphorylation.
The RIPE3b1 DNA binding factor plays a critical role in pancreatic islet beta cell-specific and glucose-regulated transcription… (More)
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2000
2000
The RIPE3b1 activator of the insulin gene is composed of a protein(s) of approximately 43 kDa, whose DNA binding activity is inhibited by protein phosphatase treatment.
Glucose-stimulated and pancreatic islet beta cell-specific expression of the insulin gene is mediated in part by the C1 DNA… (More)
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1996
1996
Chronic exposure of betaTC-6 cells to supraphysiologic concentrations of glucose decreases binding of the RIPE3b1 insulin gene transcription activator.
We have shown previously that chronic exposure of HIT-T15 cells to supraphysiologic glucose concentrations causes decreased… (More)
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1995
1995
The role of the insulin control element and RIPE3b1 activators in glucose-stimulated transcription of the insulin gene.
The most important regulator of insulin expression in islet beta-cells is glucose, which stimulates insulin gene transcription… (More)
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1994
1994
Glucose-induced transcription of the insulin gene is mediated by factors required for beta-cell-type-specific expression.
The insulin gene is expressed exclusively in pancreatic islet beta cells. The principal regulator of insulin gene transcription… (More)
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