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MAFA gene

Known as: V-MAF AVIAN MUSCULOAPONEUROTIC FIBROSARCOMA ONCOGENE HOMOLOG A, RIPE3b1, hMafA 
This gene plays a role in the regulation of insulin gene expression.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Pancreatic β-cell-restricted expression of insulin is established through several critical cis-regulatory elements located in the… Expand
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2007
2007
Transcription factors, such as PDX-1, that normally mediate pancreatic development are capable of inducing hepatic progenitor… Expand
Highly Cited
2006
Highly Cited
2006
Major insulin gene transcription factors, such as PDX-1 or NeuroD1, have equally important roles in pancreatic development and… Expand
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Highly Cited
2002
Highly Cited
2002
Of the three critical enhancer elements that mediate β-cell-specific and glucose-responsive expression of the insulin gene, only… Expand
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2001
2001
Transcription factors binding the insulin enhancer region, RIPE3b, mediate β-cell type-specific and glucose-responsive expression… Expand
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2001
2001
The RIPE3b1 DNA binding factor plays a critical role in pancreatic islet β cell-specific and glucose-regulated transcription of… Expand
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2000
2000
Glucose-stimulated and pancreatic islet β cell-specific expression of the insulin gene is mediated in part by the C1 DNA-element… Expand
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Highly Cited
1996
Highly Cited
1996
We have shown previously that chronic exposure of HIT-T15 cells to supraphysiologic glucose concentrations causes decreased… Expand
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Highly Cited
1995
Highly Cited
1995
The most important regulator of insulin gene expression in pancreatic beta- cells is glucose, which affects gene transcription… Expand
Highly Cited
1994
Highly Cited
1994
The insulin gene is expressed exclusively in pancreatic islet beta cells. The principal regulator of insulin gene transcription… Expand