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MAFA gene

Known as: V-MAF AVIAN MUSCULOAPONEUROTIC FIBROSARCOMA ONCOGENE HOMOLOG A, RIPE3b1, hMafA 
This gene plays a role in the regulation of insulin gene expression.
National Institutes of Health

Related topics

Related topics

4 relations
Homo sapiensMAFA protein, humanTranscriptional Regulationdna binding

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Clinical Scale Manufacturing Of Autologous Insulin Producing Liver Cells For The Treatment Of Diabetes
Diabetes is a major global health problem with over 387 million diabetics causing 4.9 million deaths worldwide. Current therapies… 
2005
2005
Regulation of insulin gene expression by overlapping DNA-binding elements.
The transcription factor MafA/RIPE3b1 is an important regulator of insulin gene expression. MafA binds to the insulin enhancer… 
2001
2001
The DNA Binding Activity of the RIPE3b1 Transcription Factor of Insulin Appears to Be Influenced by Tyrosine Phosphorylation*
The RIPE3b1 DNA binding factor plays a critical role in pancreatic islet β cell-specific and glucose-regulated transcription of… 
1998
1998
Identification and characterization of a glucose-responsiveness region upstream of human insulin gene in transfected HIT-T 15 cells.
To determine possible regulation of full-length human insulin gene promoter activity by glucose, we examined a 2-kilobase pair… 
Highly Cited
1994
Highly Cited
1994
Glucose-induced transcription of the insulin gene is mediated by factors required for beta-cell-type-specific expression
The insulin gene is expressed exclusively in pancreatic islet beta cells. The principal regulator of insulin gene transcription… 
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