MAD2L2 gene

Known as: MAD2B, MAD2 mitotic arrest deficient-like 2 (yeast), POLZ2 
This gene plays a role in both DNA translesion synthesis and the mitotic spindle assembly checkpoint.
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
Appropriate repair of DNA lesions and the inhibition of DNA repair activities at telomeres are crucial to prevent genomic… (More)
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Highly Cited
2007
Highly Cited
2007
The gut epithelium self-renews every several days, providing an important innate defense system that limits bacterial… (More)
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Highly Cited
2006
Highly Cited
2006
PURPOSE Most breast cancers have chromosomal instability that seems related to defective mitotic spindle checkpoints. Because the… (More)
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2006
2006
The Saccharomyces cerevisiae REV3/7-encoded polymerase zeta and Rev1 are central to the replicative bypass of DNA lesions, a… (More)
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2006
2006
DNA polymerase zeta (Polzeta) and Rev1 contribute to the bypassing of DNA lesions, termed translesion DNA synthesis (TLS… (More)
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Highly Cited
2001
Highly Cited
2001
Exit from mitosis requires the degradation of regulatory proteins including the mitotic cyclins and securin through… (More)
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Highly Cited
1998
Highly Cited
1998
Abasic (AP) sites arise in DNA through spontaneous base loss and enzymatic removal of damaged bases. APN1 encodes the major AP… (More)
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Highly Cited
1997
Highly Cited
1997
Damage-inducible mutagenesis in prokaryotes is largely dependent upon the activity of the UmuD'C-like proteins. Since many DNA… (More)
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Highly Cited
1996
Highly Cited
1996
MUTAGENESIS induced by DNA damage in Saccharomyces cerevisiae requires the products of the REV1, REV3 and REV7 genes1. The Rev3… (More)
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Review
1996
Review
1996
DNA damage induced mutations arising during the course of translesion replication are likely to be an important contributory… (More)
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