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MAC321

Known as: MAC 321, MAC-321 
National Institutes of Health

Papers overview

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2009
2009
Taxane analogue milataxel have been shown to bound to proteins/tissues irreversibly. Extraction of the aforementioned bound drug… Expand
Highly Cited
2006
Highly Cited
2006
Resistance to paclitaxel-based therapy is frequently encountered in the clinic. The mechanisms of intrinsic or acquired… Expand
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2006
2006
PurposeMAC-321 is a novel taxane that has demonstrated exceptional activity in human xenograft models when administered… Expand
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2006
2006
7098 Background: M (TL139, MAC-321) is a novel taxane that has shown activity when administered IV or orally in both taxane… Expand
2006
2006
515 Background: The slow growing cell population of solid tumors that is associated with hypoxia presents a formidable mode of… Expand
2006
2006
2037 Background: M (TL139, MAC-321) is a novel taxane with activity in human xenograft models against tumors resistant to… Expand
Highly Cited
2004
Highly Cited
2004
Current approaches for treating cancer are limited, in part, by the inability of drugs to affect the poorly vascularized regions… Expand
2004
2004
2040 Background: MAC-321 is a novel taxane that has demonstrated exceptional activity in human xenograft models when administered… Expand
Highly Cited
2003
Highly Cited
2003
The taxanes, paclitaxel (PTX) and docetaxel (DTX), belong to a novel class of anticancer drugs that stabilize microtubules and… Expand
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