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M55551

National Institutes of Health

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Broader (1)

Piperazines

Papers overview

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2006
2006
Pharmacological characterization of the active synthetic factor Xa inhibitors M55551 and M55165.
2004
2004
Synthesis and evaluation of 1-arylsulfonyl-3-piperazinone derivatives as factor Xa inhibitors III. Effect of ring opening of piperazinone moiety on inhibition.
Compounds containing an ethylenediamine structure in place of the piperazine ring of M55113 (1) and M55551 (2) were synthesized… 
2002
2002
Synthesis and evaluation of 1-arylsulfonyl-3-piperazinone derivatives as a factor Xa inhibitor II. Substituent effect on biological activities.
Intravascular clot formation is an important event in a number of cardiovascular diseases. The prevention of blood coagulation… 
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