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M 79175

Known as: M-79175, M79175, Spiro(4H-1-benzopyran-4,4'-imidazolidine)-2',5'-dione, 6-fluoro-2,3-dihydro-2-methyl- 
National Institutes of Health

Related topics

Related topics

3 relations

Narrower (1)

E 0722

Broader (2)

Enzyme InhibitorsImidazolidines

Papers overview

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1998
1998
Dose-dependent prevention of sugar cataracts in galactose-fed dogs by the aldose reductase inhibitor M79175.
Sugar cataracts rapidly develop in dogs fed a diet containing 30% galactose. While studies on the formation and progression of… 
1997
1997
Dose-dependent reduction of retinal vessel changes associated with diabetic retinopathy in galactose-fed dogs by the aldose reductase inhibitor M79175.
The onset and progression of retinal vascular changes associated with early diabetic retinopathy has been delayed in beagles fed… 
1988
1988
Polymorphic differences in alpha- and beta-form crystals of 2R, 4S, 6-fluoro-2-methyl-spiro[chroman-4,4'-imidazoline]-2',5-dione (M79175) as determined by X-ray diffraction, infrared spectroscopy…
Polymorphic differences in alpha- and beta-form crystals of 2R, 4S, 6-fluoro-2-methyl-spiro[chroman-4,4'-imidazoline]-2',5-dione… 
1987
1987
Inhibition of aldose reductase from human retina.
Aldose reductase was prepared from a pool of 21 male and 16 female human retinas by ammonium sulphate fractionation (40-75… 
1987
1987
Evaluation of orally administered activated charcoal on intestinal dialysis of intravenously administered M79175, an aldose reductase inhibitor, in rats.
The effect of oral administration of activated charcoal on serum elimination of 14C-M79175 injected intravenously in rats was… 
1986
1986
Corneal permeability of aldose reductase inhibitor, M79175. I. In vitro study using corneal permeability apparatus.
Transcorneal permeability of M79175, aldose reductase inhibitor (Eisai), and various factors influencing it were examined using… 
1986
1986
Corneal permeability of aldose reductase inhibitor, M79175. II. In vivo study on pharmacokinetic aspect.
Transcorneal permeability of M79175 was estimated in vivo and the effects of pH and thickening agent on it were examined. The… 
1982
1982
[Effects of M79175, an aldose reductase inhibitor, on experimental sugar cataracts].
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