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Lysine-tRNA Ligase

Known as: Synthetase, Lysyl-tRNA, Lysyl-tRNA Synthetase, Ligase, Lysine-tRNA 
An enzyme that activates lysine with its specific transfer RNA. EC 6.1.1.6.
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Lysyl-tRNA synthetase (LysRS), a component of the translation apparatus, is released from the cytoplasmic multi-tRNA synthetase… Expand
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Highly Cited
2012
Highly Cited
2012
Summary With renewed calls for malaria eradication, next-generation antimalarials need be active against drug-resistant parasites… Expand
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Highly Cited
2010
Highly Cited
2010
Aminoacyl-tRNA synthetase (aaRS) paralogs with unknown functions exist in various species. We now report novel 'protein… Expand
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Review
2010
Review
2010
Human immunodeficiency virus 1 (HIV‐1) uses a host cell tRNALys,3 molecule to prime reverse transcription of the viral RNA genome… Expand
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Highly Cited
2005
Highly Cited
2005
ABSTRACT Reports of the biological multifunctional activity of various aminoacyl tRNA synthetases have recently accumulated in… Expand
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Highly Cited
2000
Highly Cited
2000
Two cDNAs encoding human lysyl-tRNA synthetase have been identified. One encodes the cytoplasmic form of the enzyme identified… Expand
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Highly Cited
2000
Highly Cited
2000
Aminoacyl-tRNA synthetases play a key role in protein biosynthesis by catalyzing the specific aminoacylation of tRNA. The energy… Expand
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Highly Cited
1997
Highly Cited
1997
Lysyl-tRNAs are essential for protein biosynthesis by ribosomal mRNA translation in all organisms. They are synthesized by lysyl… Expand
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Highly Cited
1996
Highly Cited
1996
The crystal structures of Thermus thermophilus lysyl‐tRNA synthetase, a class IIb aminoacyl‐tRNA synthetase, complexed with… Expand
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Highly Cited
1985
Highly Cited
1985
Mutations in three Escherichia coli K-12 genes were isolated that reduce the efficiency of the lysine-inserting nonsense… Expand
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