Lysine-tRNA Ligase

Known as: Synthetase, Lysyl-tRNA, Lysyl-tRNA Synthetase, Ligase, Lysine-tRNA 
An enzyme that activates lysine with its specific transfer RNA. EC 6.1.1.6.
National Institutes of Health

Papers overview

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2013
2013
Lysyl-tRNA synthetase (LysRS), a component of the translation apparatus, is released from the cytoplasmic multi-tRNA synthetase… (More)
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2013
2013
Previously, DFNB89, a locus associated with autosomal-recessive nonsyndromic hearing impairment (ARNSHI), was mapped to… (More)
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Highly Cited
2012
Highly Cited
2012
With renewed calls for malaria eradication, next-generation antimalarials need be active against drug-resistant parasites and… (More)
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Highly Cited
2010
Highly Cited
2010
Aminoacyl-tRNA synthetase (aaRS) paralogs with unknown functions exist in various species. We now report novel 'protein… (More)
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Review
2010
Review
2010
Human immunodeficiency virus 1 (HIV-1) uses a host cell tRNA(Lys,3) molecule to prime reverse transcription of the viral RNA… (More)
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2004
2004
In vitro transcription has proven to be a successful tool for preparation of functional RNAs, especially in the tRNA field, in… (More)
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Highly Cited
2000
Highly Cited
2000
Two cDNAs encoding human lysyl-tRNA synthetase have been identified. One encodes the cytoplasmic form of the enzyme identified… (More)
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1997
1997
Lysyl-tRNAs are essential for protein biosynthesis by ribosomal mRNA translation in all organisms. They are synthesized by lysyl… (More)
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1996
1996
The crystal structures of Thermus thermophilus lysyl-tRNA synthetase, a class IIb aminoacyl-tRNA synthetase, complexed with… (More)
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1985
1985
Mutations in three Escherichia coli K-12 genes were isolated that reduce the efficiency of the lysine-inserting nonsense… (More)
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