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Lysine-tRNA Ligase

Known as: Synthetase, Lysyl-tRNA, Lysyl-tRNA Synthetase, Ligase, Lysine-tRNA 
An enzyme that activates lysine with its specific transfer RNA. EC 6.1.1.6.
National Institutes of Health

Related topics

Related topics

10 relations
In BloodKARS geneProcess of secretionantagonists & inhibitors

Narrower (2)

KRS protein, humanlysX protein, Mycobacterium tuberculosis

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
Lysyl-tRNA Synthetase-generated Lysyl-Adenylate Is a Substrate for Histidine Triad Nucleotide Binding Proteins*
Histidine triad nucleotide binding proteins (Hints) are the most ancient members of the histidine triad protein superfamily of… 
2007
2007
Engineered Monomeric Human Histidine Triad Nucleotide-binding Protein 1 Hydrolyzes Fluorogenic Acyl-adenylate and Lysyl-tRNA Synthetase-generated Lysyl-adenylate*
Hint1 is a homodimeric protein and member of the ubiquitous HIT superfamily. Hint1 catalyzes the hydrolysis of purine… 
2005
2005
Inhibition of Cellular HIV-1 Protease Activity by Lysyl-tRNA Synthetase*
During early assembly of human immunodeficiency virus type 1 (HIV-1), an assembly complex is formed, the components of which… 
2002
2002
Targeting of tRNA into yeast and human mitochondria: the role of anticodon nucleotides.
1994
1994
Autoantibodies to a transfer RNA-associated protein in a murine model of chronic graft versus host disease.
We established chronic graft vs host disease (GVHD) in (C57BL/10 x DBA/2)F1 mice with an injection of lymphoid cells from the… 
Highly Cited
1992
Highly Cited
1992
Autoregulation of the yeast lysyl-tRNA synthetase gene GCD5/KRS1 by translational and transcriptional control mechanisms
Highly Cited
1990
Highly Cited
1990
Roles of the two lysyl-tRNA synthetases of Escherichia coli: analysis of nucleotide sequences and mutant behavior
The complete nucleotide sequence of lysU, the gene for the heat-inducible lysyl-tRNA synthetase of Escherichia coli, was… 
1987
1987
Mapping of the constitutive lysyl-tRNA synthetase gene of Escherichia coli K-12
The constitutive lysyl-tRNA synthetase gene (lysS) was mapped at 62.1 min on the Escherichia coli chromosome by a combination of… 
1987
1987
Lysyl-tRNA synthetase from Escherichia coli K12. Chromatographic heterogeneity and the lysU-gene product.
In contrast with most aminoacyl-tRNA synthetases, the lysyl-tRNA synthetase of Escherichia coli is coded for by two genes, the… 
1969
1969
Complex formation between lysyl transfer RNA synthetase and polyuridylic acid.
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