Skip to search formSkip to main contentSkip to account menu

Lysine-Specific Demethylase 6A

Known as: KDM6A protein, human, EC 1.14.11.-, UTX protein, human 
Lysine-specific demethylase 6A (1401 aa, ~154 kDa) is encoded by the human KDM6A gene. This protein is involved in the demethylation of histone H3.
National Institutes of Health

Related topics

Related topics

12 relations
Cell NucleusEnzyme GeneHistone Demethylase JMJD3KDM5A gene

Broader (2)

Histone DemethylasesNuclear Proteins

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
MBD3/NuRD loss participates with KDM6A program to promote DOCK5/8 expression and Rac GTPase activation in human acute myeloid leukemia
Cancer genome sequencing studies have focused on identifying oncogenic mutations. However, mutational profiling alone may not… 
2019
2019
Genes upregulated in the amnion at labour are bivalently marked by activating and repressive histone modifications
Inflammatory genes are expressed increasingly in the foetal membranes at late gestation triggering birth. Here we have examined… 
2018
2018
Molecular profiling analysis for colorectal cancer patients with Pi-Xu or Shi-Re syndrome
2018
2018
DISORDERED HISTONE METHYLATION IN HEMATOLOGICAL MALIGNANCIES THE CASE OF UTX/KDM6A.
Alterations of epigenetic proteins that modulate the gene repressive lysine 27 on histone H3 (H3K27me) are recurrent features in… 
2017
2017
Re: Loss of Tumor Suppressor KDM6A Amplifies PRC2-Regulated Transcriptional Repression in Bladder Cancer and Can be Targeted through Inhibition of EZH2.
2017
2017
High Frequency of Subclonal Myeloid Mutations Can be Found in Large Granular Lymphocyte Leukemia
Large granular lymphocyte (LGL) leukemia is a clonal lymphoproliferation of cytotoxic T-lymphocytes often associated with immune… 
2016
2016
Molecular subgroups of pancreatic cancer.
2016
2016
Abstract 94: Genomic landscape and clonal expansions of upper urinary tract urothelial carcinoma
Backgrounds Upper urinary tract urothelial carcinoma (UUTUC) is a relatively rare and poor prognostic cancer which accounts for 5… 
2016
2016
Abstract 5120: The novel claudin-low molecular subtype of high-grade urothelial bladder cancer is highly immunogenic yet immunosuppressed
Rationale: High-grade urothelial carcinoma of the bladder is a heterogeneous disease, with molecular subtypes characterized by… 
2016
2016
Re: Whole-Exome Sequencing of Muscle-Invasive Bladder Cancer Identifies Recurrent Mutations of UNC5C and Prognostic Importance of DNA Repair Gene Mutations on Survival.
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)