Histone Demethylase JMJD3

Known as: JmjC Domain-Containing Protein 3, EC 1.14.11.-, Lysine-Specific Demethylase 6B 
Lysine-specific demethylase 6B (1643 aa, ~177 kDa) is encoded by the human KDM6B gene. This protein is involved in both demethylation of histone H3… (More)
National Institutes of Health

Papers overview

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2019
2019
Human glioblastoma (GBM) is the most aggressive malignancy of the CNS, with less than 5% survival. Despite great efforts to find… (More)
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2018
2018
Interleukin 4 (IL4) is generally viewed as a Th2 cytokine capable of polarizing macrophages into an anti-inflammatory phenotype… (More)
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2017
2017
Glioma is regarded as the most prevalent malignant carcinoma of the central nervous system, and lack of effective treatment. Thus… (More)
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2017
2017
Calcitriol, also known as 1,25-dihydroxyvitamin D3 (1,25(OH)2VD3), is a biologically active form of vitamin D and has a wide… (More)
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2016
2016
Harnessing epigenetic regulation is crucial for the efficient and proper differentiation of pluripotent stem cells (PSCs) into… (More)
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2016
2016
Nickel compounds are an important class of environmental pollutants and carcinogens. Chronic exposure to nickel compounds has… (More)
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2015
2015
Deregulation of pro-inflammation signals plays an important role in MDS and AML. We have previously demonstrated that the histone… (More)
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2013
2013
JMJD3, a Jumonji C family histone demethylase, plays an important role in the regulation of inflammation induced by the… (More)
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