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Histone Demethylase JMJD3

Known as: JmjC Domain-Containing Protein 3, EC 1.14.11.-, Lysine-Specific Demethylase 6B 
Lysine-specific demethylase 6B (1643 aa, ~177 kDa) is encoded by the human KDM6B gene. This protein is involved in both demethylation of histone H3… 
National Institutes of Health

Related topics

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12 relations
Cell Differentiation processDevelopmental processEnzyme GeneHomo sapiens

Papers overview

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2017
2017
Calcitriol induces cell senescence of kidney cancer through JMJD3 mediated histone demethylation
Calcitriol, also known as 1,25-dihydroxyvitamin D3 (1,25(OH)2VD3), is a biologically active form of vitamin D and has a wide… 
2015
2015
Pharmacological Inhibition of Histone Demethylase JMJD3 Reduces Leukemia Cell Survival and Represses Production of the Cytokine CCL2 in MDS/AML
Deregulation of pro-inflammation signals plays an important role in MDS and AML. We have previously demonstrated that the histone… 
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