Histone Demethylase JMJD3
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Human glioblastoma (GBM) is the most aggressive malignancy of the CNS, with less than 5% survival. Despite great efforts to find… Expand Interleukin 4 (IL4) is generally viewed as a Th2 cytokine capable of polarizing macrophages into an anti-inflammatory phenotype… Expand Glioma is regarded as the most prevalent malignant carcinoma of the central nervous system, and lack of effective treatment. Thus… Expand Calcitriol, also known as 1,25-dihydroxyvitamin D3 (1,25(OH)2VD3), is a biologically active form of vitamin D and has a wide… Expand Harnessing epigenetic regulation is crucial for the efficient and proper differentiation of pluripotent stem cells (PSCs) into… Expand Nickel compounds are an important class of environmental pollutants and carcinogens. Chronic exposure to nickel compounds has… Expand Deregulation of pro-inflammation signals plays an important role in MDS and AML. We have previously demonstrated that the histone… Expand JMJD3, a Jumonji C family histone demethylase, plays an important role in the regulation of inflammation induced by the… Expand