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Lysine-Specific Demethylase 5B

Known as: PUT 1, PLU-1 Protein, PUT1 
Lysine-specific demethylase 5B (1544 aa, ~176 kDa) is encoded by the human KDM5B gene. This protein plays a role in both histone modification and… 
National Institutes of Health

Related topics

Related topics

13 relations
ARID DomainEnzyme GeneKDM5A geneKDM5B gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
[Expression Levels of JARID1B, Hes1 and MMP-9 Genes in CML Patients Treated with Imatinib Mesylate].
OBJECTIVE To explore the relationship between the expression levels of JARID1B,Hes1 and MMP-9 genes and the stages of chronic… 
2018
2018
Jarid1b protects from metformin-induced chemosensitization to cisplatin through p53 downregulation in NSCLC
Background: Instead of nontransformed cells, tumor cells use the glycolytic pathway as their main energetic source, even when… 
2017
2017
Targeting JARID1B’s demethylase activity blocks a subset of its functions in oral cancer
Upregulation of the H3K4me3 demethylase JARID1B is linked to acquisition of aggressive, stem cell-like features by many cancer… 
2015
2015
Impairment of Preimplantation Porcine Embryo Development by Histone Demethylase KDM5B Knockdown Through Disturbance of Bivalent H3K4me3-H3K27me3 Modifications1
ABSTRACT KDM5B (JARID1B/PLU1) is a H3K4me2/3 histone demethylase that is implicated in cancer development and proliferation and… 
2015
2015
Epigenetic Regulation of Angiogenesis by JARID1B-Induced Repression of HOXA5
Objective— Altering endothelial biology through epigenetic modifiers is an attractive novel concept, which is, however, just in… 
2015
2015
JARID1B deletion induced apoptosis in Jeko-1 and HL-60 cell lines.
AIMS To investigate the involvement of JARID1B histone methyltransferase in the epigenetic change of euchromatic promoter in… 
2010
2010
The flexible loop L1 of the H3K4 demethylase JARID1B ARID domain has a crucial role in DNA-binding activity.
2004
2004
Humoral immune response against melanoma antigens induced by vaccination with cytokine gene‐modified autologous tumor cells
Although the existence of a humoral response against tumor‐associated antigens is well appreciated, a systematic analysis of its… 
2002
2002
Relevance of c-erbB2, PLU-1 and survivin mRNA expression to diagnostic assessment of breast cancer.
The positivity rates of mRNA expression in breast cancer of the tumor-related genes for c-erbB2, PLU-1 and survivin are unclear… 
1999
1999
Deficiency of a novel retinoblastoma binding protein 2-homolog is a consistent feature of sporadic human melanoma skin cancer.
Using RNA arbitrarily primed PCR, the authors selected for transcripts with cell cycle-related differential expression in… 
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