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Ly-2127399

Known as: LY2127399, LY3022859 
 
National Institutes of Health

Papers overview

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2017
2017
PurposeLY3022859 is an anti-TGFβRII IgG1 monoclonal antibody that inhibits receptor-mediated signaling activation. The primary… Expand
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2016
2016
B‐cell activating factor (BAFF) promotes the survival and adhesion of multiple myeloma (MM) cells. Tabalumab (LY2127399) is an… Expand
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Review
2015
Review
2015
Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) comprises several clinical entities with diverse clinical… Expand
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Review
2013
Review
2013
The third part of this in-depth review series on the treatment of multiple sclerosis (MS) with monoclonal antibodies covers the… Expand
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2013
2013
Background Patients with rheumatoid arthritis (RA) exhibit substantial variability in both the magnitude and duration of their… Expand
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Review
2012
Review
2012
  • W. Stohl
  • Current Rheumatology Reports
  • 2012
  • Corpus ID: 42980394
For the first time in more than 50 years, the US Food and Drug Administration has approved a drug specifically for the treatment… Expand
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2011
2011
8012 Background: LY2127399 (LY) is a human mAb that neutralizes membrane-bound and soluble B cell activating factor (BAFF). LY… Expand
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Review
2011
Review
2011
Myeloma bone disease (BD) not only impairs quality of life, but is also associated with impaired survival. Studies of the biology… Expand
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Review
2010
Review
2010
  • M. Buttmann
  • Expert review of neurotherapeutics
  • 2010
  • Corpus ID: 24588796
Treating multiple sclerosis (MS) with monoclonal antibodies (mAbs) has been marked by both progress and setbacks in the past 2… Expand
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