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tabalumab
Known as:
Anti-BAFF Monoclonal Antibody LY2127399
A human IgG4 monoclonal antibody against B-cell activating factor (BAFF), with potential immunomodulating and antineoplastic activities. Tabalumab…
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National Institutes of Health
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Related topics
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4 relations
Narrower (1)
Ly-2127399
Broader (1)
Monoclonal Antibodies
NCIt Antineoplastic Agent Terminology
antigen binding
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2013
Review
2013
B-cell biology and development.
Kathrin Pieper
,
B. Grimbacher
,
H. Eibel
Journal of Allergy and Clinical Immunology
2013
Corpus ID: 24012069
Review
2011
Review
2011
Murine Models of Systemic Lupus Erythematosus
D. Perry
,
Allison L Sang
,
Yiming Yin
,
Ying-Yi Zheng
,
L. Morel
Journal of Biomedicine and Biotechnology
2011
Corpus ID: 1012801
Systemic lupus erythematosus (SLE) is a multifactorial autoimmune disorder. The study of diverse mouse models of lupus has…
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Highly Cited
2005
Highly Cited
2005
TACI and BAFF-R mediate isotype switching in B cells
E. Castigli
,
S. Wilson
,
+6 authors
R. Geha
Journal of Experimental Medicine
2005
Corpus ID: 18878387
The tumor necrosis factor family members BAFF and APRIL induce Ig isotype switching in human B cells. We analyzed the ability of…
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Review
2005
Review
2005
The role of APRIL and BAFF in lymphocyte activation.
P. Schneider
Current Opinion in Immunology
2005
Corpus ID: 12191830
Highly Cited
2004
Highly Cited
2004
Expression of BCMA, TACI, and BAFF-R in multiple myeloma: a mechanism for growth and survival.
A. Novak
,
J. Darce
,
+6 authors
D. Jelinek
Blood
2004
Corpus ID: 19457714
Multiple myeloma (MM) is a progressive disease that is thought to result from multiple genetic insults to the precursor plasma…
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Highly Cited
2004
Highly Cited
2004
TNF Family Member B Cell-Activating Factor (BAFF) Receptor-Dependent and -Independent Roles for BAFF in B Cell Physiology1
Y. Sasaki
,
S. Casola
,
J. Kutok
,
K. Rajewsky
,
M. Schmidt-Supprian
Journal of Immunology
2004
Corpus ID: 41580105
The cytokine TNF family member B cell-activating factor (BAFF; also termed BLyS) is essential for B cell generation and…
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Highly Cited
2004
Highly Cited
2004
B Cell-Activating Factor Belonging to the TNF Family (BAFF)-R Is the Principal BAFF Receptor Facilitating BAFF Costimulation of Circulating T and B Cells1
L. Ng
,
Andrew P. R. Sutherland
,
+13 authors
C. Mackay
Journal of Immunology
2004
Corpus ID: 5774301
BAFF (B cell-activating factor belonging to the TNF family) is a cell survival and maturation factor for B cells, and…
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Highly Cited
2003
Highly Cited
2003
BAFF selectively enhances the survival of plasmablasts generated from human memory B cells.
D. Avery
,
S. Kalled
,
+7 authors
S. Tangye
Journal of Clinical Investigation
2003
Corpus ID: 24065942
The generation of Ig-secreting cells (ISCs) from memory B cells requires interactions between antigen-specific (Ag-specific) B…
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Highly Cited
2001
Highly Cited
2001
An Essential Role for BAFF in the Normal Development of B Cells Through a BCMA-Independent Pathway
Barbara J. Schiemann
,
J. Gommerman
,
+5 authors
M. Scott
Science
2001
Corpus ID: 7033307
The B cell activating factor BAFF (BlyS/TALL-1/zTNF4) is a tumor necrosis factor (TNF)–related ligand that promotes B cell…
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Highly Cited
2001
Highly Cited
2001
BAFF-R, a Newly Identified TNF Receptor That Specifically Interacts with BAFF
J. Thompson
,
S. Bixler
,
+13 authors
C. Ambrose
Science
2001
Corpus ID: 42673198
B cell homeostasis has been shown to critically depend on BAFF, the B cell activation factor from the tumor necrosis factor (TNF…
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