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Luteinizing Hormone, beta Subunit

Known as: Luteinizing Hormone, beta Polypeptide Chain, LH-beta, Lutropin beta 
The beta subunit of luteinizing hormone. It is a 15-kDa glycopolypeptide with structure similar to the beta subunit of the placental chorionic… Expand
National Institutes of Health

Related topics

Related topics

14 relations
Glycoprotein Hormones, alpha SubunitIn BloodLHB geneLutropin alfa
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Phor14-betaLHhecate-betaLH

Papers overview

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Highly Cited
2005
Highly Cited
2005
Zebrafish Gonadotropins and Their Receptors: II. Cloning and Characterization of Zebrafish Follicle-Stimulating Hormone and Luteinizing Hormone Subunits—Their Spatial-Temporal Expression Patterns and…
Abstract Gonadotropins, follicle-stimulating hormone (FSH), and luteinizing hormone (LH) play critical roles in vertebrate… Expand
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Highly Cited
2003
Highly Cited
2003
Differential regulation of gonadotropin subunit gene promoter activity by pulsatile gonadotropin-releasing hormone (GnRH) in perifused L beta T2 cells: role of GnRH receptor concentration.
The pulsatile release of GnRH by the hypothalamus is required to stimulate the pituitary-gonadal axis, and variations in GnRH… Expand
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Highly Cited
1997
Highly Cited
1997
Differential effects of gonadotropin-releasing hormone (GnRH) pulse frequency on gonadotropin subunit and GnRH receptor messenger ribonucleic acid levels in vitro.
The hypothalamic hormone, GnRH, is released and transported to the anterior pituitary in a pulsatile manner, where it binds to… Expand
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Highly Cited
1996
Highly Cited
1996
Luteinizing Hormone Deficiency and Female Infertility in Mice Lacking the Transcription Factor NGFI-A (Egr-1)
The immediate-early transcription factor NGFI-A (also called Egr-1, zif/268, or Krox-24) is thought to couple extracellular… Expand
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Highly Cited
1996
Highly Cited
1996
Steroid and pulsatile gonadotropin-releasing hormone (GnRH) regulation of luteinizing hormone and GnRH receptor in a novel gonadotrope cell line.
Properties of a pituitary gonadotrope include the capacity to regulate gonadotropin synthesis and secretion in response to a GnRH… Expand
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Highly Cited
1996
Highly Cited
1996
A Steroidogenic Factor-1 Binding Site Is Required for Activity of the Luteinizing Hormone Subunit Promoter in Gonadotropes of Transgenic Mice (*)
Analysis of luteinizing hormone (LH) β subunit promoters from a broad range of species including teleosts and humans revealed… Expand
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Highly Cited
1995
Highly Cited
1995
Targeted overexpression of luteinizing hormone in transgenic mice leads to infertility, polycystic ovaries, and ovarian tumors.
Hypersecretion of luteinizing hormone (LH) is implicated in infertility and miscarriages in women. A lack of animal models has… Expand
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Highly Cited
1994
Highly Cited
1994
Identification of two point mutations in the gene coding luteinizing hormone (LH) beta-subunit, associated with immunologically anomalous LH variants.
To analyze the structure of LH in three patients with immunologically anomalous LH, the whole coding region of the LH beta… Expand
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Highly Cited
1989
Highly Cited
1989
The frequency of gonadotropin-releasing-hormone stimulation differentially regulates gonadotropin subunit messenger ribonucleic acid expression.
The hypothalamic decapeptide GnRH is known to regulate the synthesis and secretion of LH and FSH by pituitary gonadotrope cells… Expand
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Highly Cited
1989
Highly Cited
1989
Expression of biologically active human follitropin in Chinese hamster ovary cells.
To study the structure-function relationships of follitropin (FSH), we expressed the hormone in a heterologous cell system. A… Expand
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