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Lsm1-7-Pat1 complex

Known as: Lsm1-7-Pat1 complex location 
A conserved protein complex that plays an important role in coupling deadenylation and decapping in the 5'-to-3' mRNA decay pathway. An example is… Expand
National Institutes of Health

Papers overview

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2016
2016
The Sm-like proteins (also known as Lsm proteins) are ubiquitous in nature and exist as hexa or heptameric RNA binding complexes… Expand
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2015
2015
The Lsm1-7-Pat1 complex binds to the 3' end of cellular mRNAs and promotes 3' end protection and 5'-3' decay. Interestingly, this… Expand
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2014
2014
A major mRNA decay pathway in eukaryotes is initiated by deadenylation followed by decapping of the oligoadenylated mRNAs and… Expand
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2014
2014
The evolutionarily conserved Lsm1-7-Pat1 complex is the most critical activator of mRNA decapping in eukaryotic cells and plays… Expand
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Highly Cited
2013
Highly Cited
2013
The decay of mRNAs is a key step in eukaryotic gene expression. The cytoplasmic Lsm1-7-Pat1 complex is a conserved component of… Expand
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2012
2012
Lsm proteins are a ubiquitous family of proteins characterized by the Sm-domain. They exist as hexa- or heptameric RNA-binding… Expand
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2009
2009
Decapping is a critical step in the conserved 5'-to-3' mRNA decay pathway of eukaryotes. The hetero-octameric Lsm1-7-Pat1 complex… Expand
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Highly Cited
2009
Highly Cited
2009
Messenger RNA decay occurs via two major pathways (3’ to 5’ and 5’ to 3’ pathways) that are conserved in all eukaryotes. A key… Expand
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