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Lsm1-7-Pat1 complex

Known as: Lsm1-7-Pat1 complex location 
A conserved protein complex that plays an important role in coupling deadenylation and decapping in the 5'-to-3' mRNA decay pathway. An example is… 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Mutagenic Analysis of the C-Terminal Extension of Lsm1
The Sm-like proteins (also known as Lsm proteins) are ubiquitous in nature and exist as hexa or heptameric RNA binding complexes… 
2014
2014
Pat1 contributes to the RNA binding activity of the Lsm1-7–Pat1 complex
The Lsm1-7-Pat1 complex enhances mRNA decapping in vivo. This study examines the RNA binding activity of Lsm1-7 and Pat1… 
Highly Cited
2013
Highly Cited
2013
Architecture of the Lsm1-7-Pat1 complex: a conserved assembly in eukaryotic mRNA turnover.
2012
2012
Both Sm-domain and C-terminal extension of Lsm1 are important for the RNA-binding activity of the Lsm1-7-Pat1 complex.
Lsm proteins are a ubiquitous family of proteins characterized by the Sm-domain. They exist as hexa- or heptameric RNA-binding… 
2009
2009
Activation of decapping involves binding of the mRNA and facilitation of the post-binding steps by the Lsm1-7-Pat1 complex.
Decapping is a critical step in the conserved 5'-to-3' mRNA decay pathway of eukaryotes. The hetero-octameric Lsm1-7-Pat1 complex… 
Highly Cited
2009
Highly Cited
2009
Lsm1-7-Pat1 complex: A link between 3’ and 5’-ends in mRNA decay?
Messenger RNA decay occurs via two major pathways (3’ to 5’ and 5’ to 3’ pathways) that are conserved in all eukaryotes. A key… 
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