Lower Limit of Quantitation

Known as: LLOQ, Lower Limit Value 
The lowest value in a possible range of values for a particular assessment.
National Institutes of Health

Papers overview

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Review
2017
Review
2017
Treatment With Ledipasvir-Sofosbuvir for 12 or 24 Weeks in Kidney Transplant Recipients With Chronic Hepatitis C Virus Genotype 1 or 4 Infection: A Randomized Trial.
Nearly 10% of kidney transplant recipients in Western countries have chronic hepatitis C virus (HCV) infection (1). The higher… (More)
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2012
2012
Use of Pharmacokinetic Data Below Lower Limit of Quantitation Values
In assessing the pharmacokinetics (PK) of therapeutic agents, studies are commonly performed to evaluate the ‘washout’ of the… (More)
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2012
2012
Standardized LC–MS/MS based steroid hormone profile-analysis
In order to overcome many limitations of immunoassays, high performance liquid chromatography-tandem mass spectrometry (HPLC-MS… (More)
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Highly Cited
2010
Highly Cited
2010
A liquid chromatography-coupled tandem mass spectrometry method for quantitation of cyclic di-guanosine monophosphate.
Cyclic di-guanosine monophosphate (c-di-GMP) represents an important ubiquitous second messenger in bacteria. It controls the… (More)
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Highly Cited
2010
Highly Cited
2010
A comprehensive hepatitis C viral kinetic model explaining cure.
We propose a model that characterizes and links the complexity and diversity of clinically observed hepatitis C viral kinetics to… (More)
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2009
2009
Development of a method for the sensitive and quantitative determination of hepcidin in human serum using LC-MS/MS.
INTRODUCTION Hepcidin, a 25-amino acid peptide hormone, plays a crucial regulatory role in iron metabolism. Elevated hepcidin has… (More)
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Highly Cited
2009
Highly Cited
2009
Chromatography-tandem mass spectrometry method for the simultaneous quantitation of metoprolol succinate and simvastatin in human plasma.
The liquid chromatographic-tandem mass spectrometry method was developed for the accurate quantitation of metoprolol succinate… (More)
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2009
2009
Automated method for the direct analysis of 8-oxo-guanosine and 8-oxo-2'-deoxyguanosine in human urine using ultraperformance liquid chromatography and tandem mass spectrometry.
The potential use of oxidative stress-induced DNA and RNA damage products as biomarkers is an important aspect of biomedical… (More)
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2007
2007
Determination of berberine in human plasma by liquid chromatography-electrospray ionization-mass spectrometry.
A liquid chromatography-electrospray ionization-mass spectrometry (LC-ESI-MS) method for the determination of berberine in human… (More)
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Highly Cited
2005
Highly Cited
2005
Quantification of antiretroviral drugs in dried blood spot samples by means of liquid chromatography/tandem mass spectrometry.
For the first time approved antiretroviral drugs, i.e. protease inhibitors (PI) and non-nucleoside reverse transcriptase… (More)
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