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Loperamide

Known as: Loperamide [Chemical/Ingredient], Loperamid, 1-Piperidinebutanamide, 4-(4-chlorophenyl)-4-hydroxy-N,N-dimethyl-alpha,alpha-diphenyl- 
A synthetic agent chemically related to the opiates with anti-diarrheal properties. Loperamide decreases gastro-intestinal motility by effects on the… 
National Institutes of Health

Related topics

Related topics

28 relations

Broader (1)

Antidiarrheals
Colonic Diseases, FunctionalConstipationDiarrheaDrug Allergy

Narrower (5)

ImodiumLoperamide / SimethiconeN-hydroxymethyl-N-desmethylloperamideT263 compound

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Prostaglandin-induced diarrhoea treated with loperamide or diphenoxylate. A double-blind study.
Loperamide was compared double-blind with diphenoxylate and a placebo in 59 women with diarrhoea due to prostaglandin… 
2004
2004
Racecadotril-is there enough evidence to recommend it for treatment of acute diarrhea?
Racecadotril is being proposed as a new “wonder” drug for the treatment of acute diarrhea in children. It is a synthetic… 
Review
2000
Review
2000
Why the enteric nervous system is important to clinicians
The enteric nervous system (ENS) is central to normal gut function and is involved in most, if not all, disorders of the luminal… 
1996
1996
Pancreatitis Caused by Loperamide Overdose
TO THE EDITOR: Loperamide is a piperidine derivative that slows gastrointestinal motility by affecting the circular and… 
1983
1983
Loperamide in severe protracted diarrhoea.
Six infants with severe life-threatening protracted diarrhoea were treated with loperamide. Steady-state perfusion studies of the… 
1983
1983
Loperamide in acute childhood diarrhoea: a double blind controlled trial.
The aim of this study was to evaluate the role of loperamide hydrochloride an opiate agonist in acute diarrhoea of early… 
1983
1983
Mechanisms of action of loperamide.
: The beneficial effect of loperamide in some children with severe protracted diarrhoea which persisted when nil by mouth, made… 
1981
1981
Effect of loperamide and naloxone on gastric acid secretion in healthy man.
The effect of acute oral administration of three different doses (4, 8, and 16 mg) of loperamide, a peripheral opiate agonist, on… 
1981
1981
A comparative study of loperamide and diphenoxylate in the treatment of chronic diarrhoea caused by intestinal resection.
A double-blind cross-over study of the antidiarrhoeal effects of loperamide and diphenoxylate in 29 patients with chronic… 
1981
1981
Toddler diarrhoea and prostaglandins
Chronic, non-specific `toddler diarrhoea' in young children is often accompanied by an increase in plasma prostaglandins… 
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