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Loperamide

Known as: Loperamide [Chemical/Ingredient], Loperamid, 1-Piperidinebutanamide, 4-(4-chlorophenyl)-4-hydroxy-N,N-dimethyl-alpha,alpha-diphenyl- 
A synthetic agent chemically related to the opiates with anti-diarrheal properties. Loperamide decreases gastro-intestinal motility by effects on the… 
National Institutes of Health

Related topics

Related topics

28 relations

Broader (1)

Antidiarrheals
Colonic Diseases, FunctionalConstipationDiarrheaDrug Allergy

Narrower (5)

ImodiumLoperamide / SimethiconeN-hydroxymethyl-N-desmethylloperamideT263 compound

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Prostaglandin-induced diarrhoea treated with loperamide or diphenoxylate. A double-blind study.
Loperamide was compared double-blind with diphenoxylate and a placebo in 59 women with diarrhoea due to prostaglandin… 
2004
2004
Racecadotril-is there enough evidence to recommend it for treatment of acute diarrhea?
Racecadotril is being proposed as a new “wonder” drug for the treatment of acute diarrhea in children. It is a synthetic… 
2001
2001
Does loperamide affect motor activity after proctocolectomy and ileal pouch–anal anastomosis?
Abstract. This study investigated the effect of loperamide on the motor function of small intestine and J-pouch. Proctocolectomy… 
Review
2000
Review
2000
Why the enteric nervous system is important to clinicians
The enteric nervous system (ENS) is central to normal gut function and is involved in most, if not all, disorders of the luminal… 
1994
1994
Traitement des diarrhées aiguës chez le nourrisson et le jeune enfant : étude contrôlée de l'activitié antidiarrhéique de L. acidophilus tués (souche LB) contre un placebo et un médicament de réf…
Durant trois annees consecutives, nous avons etudie, chez des enfants presentant un syndrome diarrheique aigu, l'efficacite de l… 
1994
1994
Loperamide intoxication in a seven-week-old pup.
A 7-w-old Samoyed-cross pup was presented with central nervous system signs approximately 18 h following administration of the… 
1986
1986
Effect of loperamide on faecal control after rectoplasty for high imperforate anus.
The effect of loperamide on faecal control after Stephens rectoplasty for high imperforate anus was studied in eight patients… 
1983
1983
Loperamide in acute childhood diarrhoea: a double blind controlled trial.
The aim of this study was to evaluate the role of loperamide hydrochloride an opiate agonist in acute diarrhoea of early… 
1983
1983
Mechanisms of action of loperamide.
: The beneficial effect of loperamide in some children with severe protracted diarrhoea which persisted when nil by mouth, made… 
1977
1977
[Effects of loperamide on the gastric and intestinal motilities in the guinea pig and dog (author's transl)].
In anesthetized dogs, intravenous administration or intrajejunal infusion of Loperamide produced the excitatory effect of gastric…