Liver, Artificial

Known as: Artificial Liver, Artificial Livers, Livers, Artificial 
Devices for simulating the activities of the liver. They often consist of a hybrid between both biological and artificial materials.

Topic mentions per year

Topic mentions per year

1960-2018
05019602018

Papers overview

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2012
2012
BACKGROUND New bioartificial liver devices are needed to supplement the limited supply of organ donors available for patients… (More)
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Highly Cited
2011
Highly Cited
2011
"Humanized" mice offer a window into aspects of human physiology that are otherwise inaccessible. The best available methods for… (More)
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2009
2009
UNLABELLED The culture of primary hepatocytes as spheroids creates an efficient three-dimensional tissue construct for hepatic… (More)
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Highly Cited
2008
Highly Cited
2008
Acute liver failure (ALF) is a rare but challenging clinical syndrome with multiple causes; a specific etiology cannot be… (More)
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2008
2008
Drug metabolism studies and liver tissue engineering necessitate stable hepatocyte cultures that express liver functions for a… (More)
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Highly Cited
2007
Highly Cited
2007
Primary hepatocytes represent a physiologically relevant model for drug toxicity screening. Here, we created a biologically… (More)
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Highly Cited
2004
Highly Cited
2004
OBJECTIVE The HepatAssist liver support system is an extracorporeal porcine hepatocyte-based bioartificial liver (BAL). The… (More)
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Highly Cited
2003
Highly Cited
2003
We have developed a perfusion bioreactor system that allows the formation of steady state oxygen gradients in cell culture. In… (More)
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Highly Cited
2002
Highly Cited
2002
We have derived from normal human, mouse, and rat postnatal bone marrow primitive, multipotent adult progenitor cells (MAPCs… (More)
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Highly Cited
1997
Highly Cited
1997
OBJECTIVE The purpose of this study was to develop a bioartificial liver (BAL) to treat patients with severe liver failure until… (More)
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