Lissencephaly

Known as: Lissencephaly [Disease/Finding], Lissencephalies, Lissencephalia 
A smooth brain malformation of the CEREBRAL CORTEX resulting from the abnormal location of developing neurons during corticogenesis. It is… (More)
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
Genes disrupted in human microcephaly (meaning "small brain") define key regulators of neural progenitor proliferation and cell… (More)
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Highly Cited
2007
Highly Cited
2007
The development of the mammalian brain is dependent on extensive neuronal migration. Mutations in mice and humans that affect… (More)
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Highly Cited
2002
Highly Cited
2002
Male embryonic mice with mutations in the X-linked aristaless-related homeobox gene (Arx) developed with small brains due to… (More)
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Highly Cited
2000
Highly Cited
2000
Mutations in the LIS1 gene cause gross histological disorganization of the developing human brain, resulting in a brain surface… (More)
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Highly Cited
1999
Highly Cited
1999
Here we show that the Drosophila homologue of Lissencephaly-1, DLis-1, acts together with Bicaudal-D (Bic-D), Egalitarian (Egl… (More)
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Highly Cited
1999
Highly Cited
1999
Recently, we and others reported that the doublecortin gene is responsible for X-linked lissencephaly and subcortical laminar… (More)
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Highly Cited
1998
Highly Cited
1998
X-linked lissencephaly and "double cortex" are allelic human disorders mapping to Xq22.3-Xq23 associated with arrest of migrating… (More)
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Highly Cited
1998
Highly Cited
1998
X-SCLH/LIS syndrome is a neuronal migration disorder with disruption of the six-layered neocortex. It consists of subcortical… (More)
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Review
1998
Review
1998
During the past 20 years, biologists have become used to finding that proteins first identified in simple, genetically… (More)
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Highly Cited
1993
Highly Cited
1993
Lissencephaly (agyria-pachygyria) is a human brain malformation manifested by a smooth cerebral surface and abnormal neuronal… (More)
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