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Liposomal Eribulin Mesylate
Known as:
E7389 Liposomal Formulation
, E7389-LF
A liposome-encapsulated formulation of the mesylate salt form of eribulin, a synthetic, macrocyclic ketone analogue of halichondrin B, a substance…
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National Institutes of Health
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Related topics
Related topics
4 relations
Microtubule Process
Microtubules
Negative Regulation of Mitosis
Tubulin
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
Phase I study of liposomal formulation of eribulin (E7389-LF) in patients (pts) with advanced solid tumours: Primary results of dose-escalation part
N. Yamamoto
,
J. Sato
,
+12 authors
Toshio Shimizu
Annals of Oncology
2019
Corpus ID: 208392935
Abstract Background Eribulin is approved for treatment of advanced/metastatic breast cancer and previously treated, unresected…
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Review
2015
Review
2015
Eribulin in Cancer Treatment
U. Swami
,
U. Shah
,
S. Goel
Marine drugs
2015
Corpus ID: 37448517
Halichondrin B is a complex, natural, polyether macrolide derived from marine sponges. Eribulin is a structurally-simplified…
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2015
2015
Abstract 4543: Characterization of the liposomal formulation of eribulin mesylate (E7389) in mice
M. Asano
,
K. Hyodo
,
+5 authors
K. Nomoto
2015
Corpus ID: 79405327
E7389 (eribulin mesylate, Halaven, Eisai) is a fully synthetic analog of the marine sponge natural product halichondrin B. It has…
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2013
2013
Characterization of the pharmacokinetics of a liposomal formulation of eribulin mesylate (E7389) in mice.
Yanke Yu
,
C. Desjardins
,
P. Saxton
,
G. Lai
,
E. Schuck
,
Y. Wong
International journal of pharmaceutics
2013
Corpus ID: 25781665
Highly Cited
2009
Highly Cited
2009
New syntheses of E7389 C14-C35 and halichondrin C14-C38 building blocks: reductive cyclization and oxy-Michael cyclization approaches.
Cheng-Guo Dong
,
J. A. Henderson
,
+6 authors
Y. Kishi
Journal of the American Chemical Society
2009
Corpus ID: 30838297
Cr-mediated coupling reactions are usually achieved with a slight excess of a given nucleophile. To develop a cost-effective use…
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Highly Cited
2009
Highly Cited
2009
New syntheses of E7389 C14-C35 and halichondrin C14-C38 building blocks: double-inversion approach.
Dae-Shik Kim
,
Cheng-Guo Dong
,
+4 authors
Y. Kishi
Journal of the American Chemical Society
2009
Corpus ID: 21282887
With sequential use of catalytic asymmetric Cr-mediated coupling reactions, E7389 C14-C35 and halichondrin C14-C38 building…
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2009
2009
Second generation synthesis of C27-C35 building block of E7389, a synthetic halichondrin analogue.
Yu-Rong Yang
,
Dae-Shik Kim
,
Y. Kishi
Organic letters
2009
Corpus ID: 207647132
A practical method is reported to synthesize E7389 C27-C35 building block 13 from 1,2-O-isopropylidene-alpha-D-5-deoxyglucurono-6…
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2007
2007
Microtubule-Stabilizing Agent: Halichondrin B Analog (E7389)
Deena M. Atieh
,
Linda T. Vahdat
2007
Corpus ID: 72613986
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