Lipoatrophy

Localized loss of fat tissue. [HPO:sdoelken]
National Institutes of Health

Papers overview

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Highly Cited
2006
Highly Cited
2006
BACKGROUND Long-term antiretroviral therapy, while dramatically reducing HIV-related morbidity and mortality, is associated with… (More)
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Highly Cited
2005
Highly Cited
2005
We describe the generation and characterization of the first inducible 'fatless' model system, the FAT-ATTAC mouse (fat apoptosis… (More)
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Highly Cited
2004
Highly Cited
2004
BACKGROUND Lipodystrophy commonly complicates antiretroviral therapy of HIV-1 infection. Thiazolidinediones such as rosiglitazone… (More)
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Highly Cited
2004
Highly Cited
2004
OBJECTIVE To determine if long-term improvement in HIV lipoatrophy can be attained by substitution of thymidine analogues… (More)
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Highly Cited
2003
Highly Cited
2003
BACKGROUND In the absence of currently available therapy to manage facial lipoatrophy, strategies used to compensate for facial… (More)
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Highly Cited
2003
Highly Cited
2003
The serine/threonine kinase Akt/PKB plays key roles in the regulation of cell growth, survival, and metabolism. It remains… (More)
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Highly Cited
2002
Highly Cited
2002
CONTEXT Peripheral lipoatrophy may complicate antiretroviral therapy of human immunodeficiency virus (HIV) infection, often… (More)
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Highly Cited
2001
Highly Cited
2001
Adiponectin is an adipocyte-derived hormone. Recent genome-wide scans have mapped a susceptibility locus for type 2 diabetes and… (More)
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Review
2000
Review
2000
The lipoatrophy syndromes are a heterogeneous group of syndromes characterized by a paucity of adipose tissue. Severe lipoatrophy… (More)
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Highly Cited
2000
Highly Cited
2000
BACKGROUND Lipodystrophy (LD; peripheral lipoatrophy, central adiposity) hyperlipidaemia and insulin resistance often complicate… (More)
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