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Levocabastine hydrochloride

Known as: 4-Piperidinecarboxylic Acid, 1-(4-cyano-4-(4-fluorophenyl)cyclohexyl)-3-methyl-4-phenyl-, Monohydrochloride,(-)-(1(cis)3alpha,4beta)-, R 50,547 
The hydrochloride salt form of levocabastine, a synthetic piperidine derivative with antihistaminic properties. Levocabastine is a second generation… 
National Institutes of Health

Related topics

Related topics

5 relations
Allergic ConjunctivitisHistamine H1 Receptor Antagonists [MoA]levocabastinelevocabastine 0.5 MG/ML Ophthalmic Suspension [Livostin]

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Livostin

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Identification of N-{[6-chloro-4-(2,6-dimethoxyphenyl)quinazolin-2-yl]carbonyl}-l-leucine (NTRC-808), a novel nonpeptide chemotype selective for the neurotensin receptor type 2.
2014
2014
The Effect of Topical Corticosteroids, Topical Antihistamines, and Preservatives on Human Ciliary Beat Frequency
Background: The aim of this study was to investigate the effect of the corticosteroids, the antihistamines, and the preservatives… 
2006
2006
Effect of antihistamine eye drops on the conjunctival provocation test with Japanese cedar pollen allergen.
BACKGROUND Approximately 16.2% of the Japanese population suffer from cedar pollinosis, with various manifestations such as… 
Review
2002
Review
2002
[Pharmacological and clinical properties of levocabastine hydrochloride (eye drop and nasal spray), a selective H1 antagonist].
Levocabastine is a selective histamine H1-receptor antagonist exerting inhibitory effects on the release of chemical mediators… 
2000
2000
Emedastine ophthalmic solution 0.05% versus levocabastine ophthalmic suspension 0.05% in the treatment of allergic conjunctivitis using the conjunctival allergen challenge model.
1996
1996
Combinaison d'antihistamines et de steroides a application topique par voie nasale
La presente invention se rapporte a un pulverisateur nasal ou a des gouttes nasales pour le traitement de rhinites allergiques… 
Review
1995
Review
1995
Allergic and atopic diseases of the lid, conjunctiva, and cornea
&NA; Ocular allergies are commonly encountered in clinical practice. The familiarity with the typical constellation of signs and… 
1994
1994
Effects of antiallergic agents including levocabastine on experimental rhinitis in rats.
Topical application of levocabastine hydrochloride (-)-[3S-[1(cis)-3 alpha,4 beta]]-1-[4-cyano-4-(4-fluorophenyl) cyclohexyl]-3… 
1993
1993
Antiallergic profile of the novel H1-antihistaminic compound levocabastine.
Levocabastine hydrochloride (R50 547, CAS79516-68-0) caused no inhibitory effect on the histamine release from rat peritoneal… 
1990
1990
Central effect of the potent long-acting H1-antihistamine levocabastine.
The effects of levocabastine (R 50 547; CAS 79516-68-0) on the central nervous system were studied in comparison with those of… 
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